CAS 107007-99-8: Granisetron Hydrochloride
Description:Granisetron Hydrochloride is a selective serotonin 5-HT3 receptor antagonist primarily used as an antiemetic to prevent nausea and vomiting associated with chemotherapy, radiation therapy, and surgery. It is a white to off-white crystalline powder that is soluble in water and exhibits a pH range typically between 4 and 6 when dissolved. The molecular formula of Granisetron Hydrochloride reflects its structure, which includes a piperidine ring, contributing to its pharmacological activity. This compound is often administered orally or intravenously, depending on the clinical scenario. Granisetron acts by blocking the action of serotonin at the 5-HT3 receptors in the gastrointestinal tract and the central nervous system, thereby inhibiting the vomiting reflex. Its pharmacokinetics indicate a relatively long half-life, allowing for effective management of nausea and vomiting with fewer doses. As with any medication, potential side effects may include headache, constipation, and dizziness, necessitating careful monitoring during treatment.
Formula:C18H24N4O
InChI:InChI=1/C18H24N4O.ClH/c1-21-13-6-5-7-14(21)11-12(10-13)19-18(23)17-15-8-3-4-9-16(15)22(2)20-17;/h3-4,8-9,12-14H,5-7,10-11H2,1-2H3,(H,19,23);1H/t12-,13+,14-;
InChI key:InChIKey=QYZRTBKYBJRGJB-WQTKJZBYNA-N
SMILES:Cl.O=C(NC1CC2N(C)C(CCC2)C1)C3=NN(C=4C=CC=CC34)C
- Synonyms:
- 1-Methyl-N-(9-Methyl-9-Azabicyclo(3.3.1)Non-3-Yl)-1H-Indazole-3-Carboxamid
- 1-Methyl-N-(9-Methyl-9-Azabicyclo[3.3.1]Non-3-Yl)-1H-Indazole-3-Carboxamide
- 1-Methyl-N-(9-Methyl-9-Azabicyclo[3.3.1]Non-3-Yl)-1H-Indazole-3-Carboxamide Hydrochloride (1:1)
- 1-Methyl-N-[(3-Endo)-9-Methyl-9-Azabicyclo[3.3.1]Non-3-Yl]-1H-Indazole-3-Carboxamide
- 1-Methyl-N-[(3-Endo)-9-Methyl-9-Azabicyclo[3.3.1]Non-3-Yl]-1H-Indazole-3-Carboxamide Hydrochloride
- 1H-Indazole-3-Carboxamide, 1-Methyl-N-(9-Methyl-9-Azabicyclo[3.3.1]Non-3-Yl)-, Monohydrochloride, Endo-
- 1H-Indazole-3-Carboxamide, 1-Methyl-N-[(3-Endo)-9-Methyl-9-Azabicyclo[3.3.1]Non-3-Yl]-, Monohydrochloride
- 1H-Indazole-3-carboxamide, 1-methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-, hydrochloride (1:1)
- 9-Azabicyclo[3.3.1]nonane, 1H-indazole-3-carboxamide deriv.
- Brl-43694A
- See more synonyms
- Brl-43694A, Kytril, 1-Methyl-N-[(3-Endo)-9-Methyl-9-Azabicyclo[3.3.1]Non-3-Yl]-1H-Indazole-3-Carboxamide Hydrochloride
- Endo-1-Methyl-N-(9-Methyl-9-Azabicyclo(3.3.1)Non-3-Yl)-1H-Indazole-3-Carboxa
- Endo-Monohydrochlorid
- Endo-Monohydrochloride
- Granisertrol Hydrochloride
- Granisertronhydrochloride
- Granisetron Hcl
- Granisetron Hydrocholride
- Granisetronhclfda
- Granisetronhydrochloridefdainspected
- Granistron Hydrochloride
- Gransetron Hcl
- Kytril
- Midehydrochloride
