CAS 107021-12-5

9-(2-Phosphonylmethoxypropyl)adenine

Description:

9-(2-Phosphonylmethoxypropyl)adenine, with the CAS number 107021-12-5, is a synthetic nucleoside analog that exhibits properties relevant to antiviral and anticancer research. This compound features a modified adenine structure, where a phosphonylmethoxypropyl group is attached at the 9-position of the adenine base. The presence of the phosphonyl group enhances its stability and bioactivity, making it a subject of interest in medicinal chemistry. Its mechanism of action typically involves interference with nucleic acid synthesis, which can inhibit viral replication or tumor cell proliferation. The compound is often studied for its potential therapeutic applications, particularly in the treatment of viral infections and certain types of cancer. Additionally, its solubility and stability in biological systems are critical for its efficacy as a drug candidate. Overall, 9-(2-Phosphonylmethoxypropyl)adenine represents a significant advancement in the development of nucleoside analogs with enhanced pharmacological properties.

Formula: C₉H₁₄N₅O₄P

InChI: InChI=1/C9H14N5O4P/c1-6(18-5-19(15,16)17)2-14-4-13-7-8(10)11-3-12-9(7)14/h3-4,6H,2,5H2,1H3,(H2,10,11,12)(H2,15,16,17)/t6-/m1/s1

SMILES: C[C@H](Cn1cnc2c(N)ncnc12)OCP(=O)(O)O

Synonyms:

• phosphonic acid, [[2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-
• ({[1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonic acid
• ({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonic acid

rac-Tenofovir-d7

CAS: 107021-12-5

Formula: C₉H₇D₇N₅O₄P

Color and Shape: White To Off-White Solid

Molecular weight: 294.26

Ref: 4Z-T-026

rac-Tenofovir

CAS: 107021-12-5

Formula: C₉H₁₄N₅O₄P

Molecular weight: 287.22

Ref: 4Z-T-02150

Rac Tenofovir

CAS: 107021-12-5

Formula: C₉H₁₄N₅O₄P

Molecular weight: 287.22

Ref: ST-EA-CP-T5035

rac Tenofovir-13C5 (>90%)

Controlled Product

CAS: 107021-12-5

Formula: C₄₁₃C₅H₁₄N₅O₄P

Purity: >90%

Color and Shape: Neat

Molecular weight: 292.18

Ref: TR-T018501