CAS 107036-62-4

4-amino-5-fluoro-1-[(2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2(1H)-one

Description:

4-amino-5-fluoro-1-[(2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2(1H)-one, with CAS number 107036-62-4, is a chemical compound that belongs to the class of pyrimidine derivatives. This substance features a pyrimidinone core, which is characterized by the presence of an amino group and a fluorine atom at specific positions on the ring. The compound also contains a tetrahydrofuran moiety, which contributes to its structural complexity and may influence its biological activity. The hydroxymethyl group on the tetrahydrofuran ring enhances its solubility and potential interactions with biological targets. This compound has garnered interest in medicinal chemistry, particularly for its potential applications in antiviral or anticancer therapies, owing to its structural similarity to nucleosides. Its specific stereochemistry, indicated by the (2R,5S) configuration, is crucial for its biological function and interaction with enzymes or receptors. Overall, this compound exemplifies the intricate relationship between molecular structure and biological activity in pharmaceutical development.

Formula: C₉H₁₂FN₃O₃

InChI: InChI=1/C9H12FN3O3/c10-6-3-13(9(15)12-8(6)11)7-2-1-5(4-14)16-7/h3,5,7,14H,1-2,4H2,(H2,11,12,15)/t5-,7+/m0/s1

Synonyms:

• 2(1H)-pyrimidinone, 4-amino-5-fluoro-1-[(2R,5S)-tetrahydro-5-(hydroxymethyl)-2-furanyl]-
• 2',3'-Dideoxy-5-fluorocytidine
• 5-Fluoro-2',3'-Dideoxycytidine

2',3'-Dideoxy-5-fluorocytidine

CAS: 107036-62-4

Nucleoside Derivatives - 2’,3’-Dideoxy-nucleoside; Fluoro-modified nucleoside; Drugs and Inhibitors; HIV-1 inhibitors

Formula: C₉H₁₂FN₃O₃

Color and Shape: Solid

Molecular weight: 229.21

Ref: TM-TNU0263

2’,3’-Dideoxy-5-fluorocytidine

CAS: 107036-62-4

2’,3’-Dideoxy-5-fluorocytidine is a nucleoside analog that inhibits the growth of tumor cells in animals. It has been shown to inhibit the replication of hepatitis B virus and HIV without affecting normal cell division. 2′,3′-Dideoxy-5-fluorocytidine also has potent antitumor activity against human hematopoietic cells and induces apoptosis.

Formula: C₉H₁₂FN₃O₃

Purity: Min. 95%

Molecular weight: 229.21 g/mol

Ref: 3D-ND99344