CAS 107097-80-3

Loxiglumide

Description:

Loxiglumide is a chemical compound primarily known for its role as a gastrointestinal motility agent and a selective antagonist of the cholecystokinin (CCK) receptor. It is classified as a non-peptide CCK antagonist, which means it can inhibit the action of CCK, a hormone that plays a crucial role in digestion and appetite regulation. Loxiglumide has been investigated for its potential therapeutic applications in conditions such as functional dyspepsia and other gastrointestinal disorders. The compound is typically characterized by its molecular structure, which includes specific functional groups that contribute to its biological activity. In terms of physical properties, Loxiglumide is usually presented as a white to off-white solid, with solubility in organic solvents. Its pharmacokinetics and safety profile have been subjects of research, highlighting its effects on gastric emptying and gastrointestinal motility. Overall, Loxiglumide represents a significant interest in pharmacology, particularly in the context of gastrointestinal health.

Formula: C₂₁H₃₀Cl₂N₂O₅

InChI: InChI=1S/C21H30Cl2N2O5/c1-3-4-5-11-25(12-6-13-30-2)21(29)18(9-10-19(26)27)24-20(28)15-7-8-16(22)17(23)14-15/h7-8,14,18H,3-6,9-13H2,1-2H3,(H,24,28)(H,26,27)

InChI key: InChIKey=QNQZBKQEIFTHFZ-UHFFFAOYSA-N

SMILES: C(C(N(CCCCC)CCCOC)=O)(NC(=O)C1=CC(Cl)=C(Cl)C=C1)CCC(O)=O

Synonyms:

• (+-)-4-((3,4-Dichlorobenzoyl)amino)-5-((3-methoxypropyl)pentylamino)-5-oxopentanoic acid
• (+-)-4-(3,4-Dichlorobenzamido)-N-(3-methoxypropyl)-N-pentylglutaramic acid
• Ccris 8590
• Cr 1505
• D,L-4-(3,4-Dichlorobenzoylamino)-5-(N-3-methoxypropylpentylamino)-5-oxo-pentanoic acid
• Loxiglumida
• Loxiglumida [Spanish]
• Loxiglumide [INN]
• Loxiglumidum
• Loxiglumidum [Latin]
• N~2~-(3,4-dichlorobenzoyl)-N-(3-methoxypropyl)-N-pentyl-alpha-glutamine
• Pentanoic acid, 4-((3,4-dichlorobenzoyl)amino)-5-((3-methoxypropyl)pentylamino)-5-oxo-, (+-)-

Loxiglumide

CAS: 107097-80-3

Formula: C₂₁H₃₀Cl₂N₂O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 461.3793

Ref: IN-DA008S1Q

Loxiglumide

CAS: 107097-80-3

Formula: C₂₁H₃₀Cl₂N₂O₅

Molecular weight: 461.38

Ref: 7W-GK9118

Loxiglumide

CAS: 107097-80-3

Loxiglumide

Purity: ≥95%

Molecular weight: 461.38g/mol

Ref: 54-BUP13667

Loxiglumide

CAS: 107097-80-3

Loxiglumide (CR-1505) is an antagonist of cholecystokinin (CCK-1) receptor.

Formula: C₂₁H₃₀Cl₂N₂O₅

Purity: 97.55% - 99.81%

Color and Shape: Solid

Molecular weight: 461.38

Ref: TM-T2312

Loxiglumide

CAS: 107097-80-3

Antagonist of CCK-A receptor

Purity: Min. 95%

Ref: 3D-BL166440