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CAS 107097-80-3

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Loxiglumide

Description:
Loxiglumide is a chemical compound primarily known for its role as a gastrointestinal motility agent and a selective antagonist of the cholecystokinin (CCK) receptor. It is classified as a non-peptide CCK antagonist, which means it can inhibit the action of CCK, a hormone that plays a crucial role in digestion and appetite regulation. Loxiglumide has been investigated for its potential therapeutic applications in conditions such as functional dyspepsia and other gastrointestinal disorders. The compound is typically characterized by its molecular structure, which includes specific functional groups that contribute to its biological activity. In terms of physical properties, Loxiglumide is usually presented as a white to off-white solid, with solubility in organic solvents. Its pharmacokinetics and safety profile have been subjects of research, highlighting its effects on gastric emptying and gastrointestinal motility. Overall, Loxiglumide represents a significant interest in pharmacology, particularly in the context of gastrointestinal health.
Formula:C21H30Cl2N2O5
InChI:InChI=1S/C21H30Cl2N2O5/c1-3-4-5-11-25(12-6-13-30-2)21(29)18(9-10-19(26)27)24-20(28)15-7-8-16(22)17(23)14-15/h7-8,14,18H,3-6,9-13H2,1-2H3,(H,24,28)(H,26,27)
InChI key:InChIKey=QNQZBKQEIFTHFZ-UHFFFAOYSA-N
SMILES:C(C(N(CCCCC)CCCOC)=O)(NC(=O)C1=CC(Cl)=C(Cl)C=C1)CCC(O)=O
Synonyms:
  • (+-)-4-((3,4-Dichlorobenzoyl)amino)-5-((3-methoxypropyl)pentylamino)-5-oxopentanoic acid
  • (+-)-4-(3,4-Dichlorobenzamido)-N-(3-methoxypropyl)-N-pentylglutaramic acid
  • Ccris 8590
  • Cr 1505
  • D,L-4-(3,4-Dichlorobenzoylamino)-5-(N-3-methoxypropylpentylamino)-5-oxo-pentanoic acid
  • Loxiglumida
  • Loxiglumida [Spanish]
  • Loxiglumide [INN]
  • Loxiglumidum
  • Loxiglumidum [Latin]
  • See more synonyms
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Found 5 products.