CAS 107188-92-1

FLB 457 Hydrobromide

Description:

FLB 457 Hydrobromide is a chemical compound primarily recognized for its role as a selective antagonist of the dopamine D2 receptor. It is often studied in the context of neuropharmacology and has potential implications for treating various neurological disorders. The hydrobromide salt form enhances its solubility and stability, making it suitable for pharmaceutical applications. FLB 457 is characterized by its specific binding affinity to the D2 receptor, which is crucial for its function in modulating dopaminergic activity in the brain. This compound is typically administered in research settings to investigate its effects on dopamine-related pathways and behaviors. Additionally, its chemical structure includes a distinct arrangement of atoms that contributes to its pharmacological properties. As with many research chemicals, safety and handling precautions are essential, as the compound may exhibit varying effects depending on dosage and administration route. Overall, FLB 457 Hydrobromide serves as a valuable tool in understanding dopamine receptor dynamics and their implications in mental health.

Formula: C₁₆H₂₄Br₂N₂O₃

InChI: InChI=1/C16H23BrN2O3.BrH/c1-4-19-7-5-6-12(19)10-18-16(20)13-8-11(17)9-14(21-2)15(13)22-3;/h8-9,12H,4-7,10H2,1-3H3,(H,18,20);1H/t12-;/m0./s1

SMILES: CCN1CCC[C@H]1CN=C(c1cc(cc(c1OC)OC)Br)O.Br

Synonyms:

• (S)-5-Bromo-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2,3-dimethoxybenzamide Monohydrobromide
• Isoremoxipride Hydrobromide
• 5-bromo-N-[[(2S)-1-ethylpyrrolidin-2-yl]methyl]-2,3-dimethoxy-benzimidic acid hydrobromide

FLB 457 Hydrobromide

Controlled Product

CAS: 107188-92-1

Applications Potential antipsychotic agent; antidopaminergic.
References Hoegberg, T., et al.: J. Med. Chem., 33, 2305 (1990), 3) Glase, S., et al.: J. Med. Chem., 40, 1771 (1997), Hansch, C., et al.: Bioorg. Med. Chem., 11, 2075 (2003), Kulkarni, S., et al.: J. Med. Chem., 47, 3388 (2004), Verma, R., et al.: Bioorg. Med. Chem., 13, 1059 (2005),

Formula: C₁₆H₂₃BrN₂O₃·BrH

Color and Shape: Neat

Molecular weight: 452.18

Ref: TR-F375000

Isoremoxipride hydrobromide

CAS: 107188-92-1

Isoremoxipride hydrobromide is a dopamine antagonist.

Formula: C₁₆H₂₄Br₂N₂O₃

Color and Shape: Solid

Molecular weight: 452.18

Ref: TM-T71496