CAS 1072944-45-6

3-Bromo-7-methoxyimidazo[1,2-a]pyridine-8-carbonitrile

Description:

3-Bromo-7-methoxyimidazo[1,2-a]pyridine-8-carbonitrile is a heterocyclic organic compound characterized by its complex structure, which includes a bromine atom, a methoxy group, and a carbonitrile functional group. The imidazo[1,2-a]pyridine framework is notable for its aromaticity and potential biological activity, making it of interest in medicinal chemistry. The presence of the bromine atom can enhance the compound's reactivity and influence its pharmacological properties, while the methoxy group may affect solubility and lipophilicity. The carbonitrile group contributes to the compound's polarity and can participate in various chemical reactions, including nucleophilic additions. This compound may exhibit interesting biological activities, potentially serving as a lead compound in drug discovery. Its unique structural features suggest potential applications in various fields, including pharmaceuticals and agrochemicals. As with many heterocycles, the synthesis and characterization of this compound are crucial for understanding its properties and potential uses.

Formula: C₉H₆BrN₃O

InChI: InChI=1S/C9H6BrN3O/c1-14-7-2-3-13-8(10)5-12-9(13)6(7)4-11/h2-3,5H,1H3

InChI key: InChIKey=FWOYBZCRIUHVID-UHFFFAOYSA-N

SMILES: C(#N)C=1C=2N(C=CC1OC)C(Br)=CN2

Synonyms:

• Imidazo[1,2-a]pyridine-8-carbonitrile, 3-bromo-7-methoxy-
• 3-Bromo-7-methoxyimidazo[1,2-a]pyridine-8-carbonitrile
• 3-Bromo-7-methoxyimidazo[1,2-a)pyridine-8-

3-Bromo-7-Methoxyimidazo[1,2-A]Pyridine-8-Carbonitrile

CAS: 1072944-45-6

Formula: C₉H₆BrN₃O

Color and Shape: Solid

Molecular weight: 252.0674

Ref: IN-DA0082EC

3-Bromo-7-methoxyimidazo[1,2-a]pyridine-8-carbonitrile

Controlled Product

CAS: 1072944-45-6

Applications 3-Bromo-7-methoxyimidazo[1,2-a]pyridine-8-carbonitrile is used in preparation of Indazole derivatives as inhibitors of Methionine Aminopeptidase 2, which is useful in treatment of obesity and related MetAP2-mediated diseases.
References Cheruvallath, Z., et al.: PCT Int. Appl. (2013), WO 2013130855 A1

Formula: C₉H₆BrN₃O

Color and Shape: Neat

Molecular weight: 252.07

Ref: TR-B696703