CAS 107429-63-0

Lintopride

Description:

Lintopride, with the CAS number 107429-63-0, is a chemical compound that belongs to the class of benzamide derivatives. It is primarily recognized for its pharmacological properties, particularly as a dopamine receptor antagonist. Lintopride exhibits a high affinity for D2 dopamine receptors, which makes it relevant in the treatment of various gastrointestinal disorders, including functional dyspepsia and gastroparesis. The compound is characterized by its ability to modulate gastrointestinal motility and has been studied for its potential effects on nausea and vomiting. In terms of its physical properties, Lintopride is typically presented as a white to off-white crystalline powder, which is soluble in certain organic solvents. Its safety profile and side effects are similar to other medications in its class, necessitating careful consideration during clinical use. Overall, Lintopride represents a significant compound in the realm of gastrointestinal pharmacotherapy, with ongoing research into its broader therapeutic applications.

Formula: C₁₄H₁₉ClN₄O₂

InChI: InChI=1/C14H19ClN4O2/c1-3-19-5-4-17-13(19)8-18-14(20)9-6-10(15)11(16)7-12(9)21-2/h6-7H,3-5,8,16H2,1-2H3,(H,18,20)

SMILES: CCN1CCN=C1CN=C(c1cc(c(cc1OC)N)Cl)O

Synonyms:

• Lintopride [INN]
• 4-Amino-5-chloro-N-((1-ethyl-2-imidazolin-2-yl)methyl)-o-anisamide
• Lintoprida
• Lintoprida [INN-Spanish]
• Lintopridum
• Lintopridum [INN-Latin]
• Unii-C2R0Geu722
• 4-amino-5-chloro-N-[(1-ethyl-4,5-dihydro-1H-imidazol-2-yl)methyl]-2-methoxybenzamide

Lintopride

CAS: 107429-63-0

Lintopride is a potent and selective blocker of the L-type Ca2+ channels. It binds to the channel protein in its open state, thereby blocking the influx of extracellular Ca2+. Lintopride is used as a research tool to study ion channels, receptor binding, ligand-receptor interactions, and protein interactions. Lintopride has been shown to activate the calcium-sensitive phospholipase A2 in erythrocytes and inhibit platelet aggregation. It also inhibits DNA synthesis in human lymphocytes.

Formula: C₁₄H₁₉ClN₄O₂

Purity: Min. 95%

Molecular weight: 310.78 g/mol

Ref: 3D-HEA42963

Lintopride

CAS: 107429-63-0

Lintopride is an antagonist of 5HT4. It has moderate 5HT3 antagonist properties.

Formula: C₁₄H₁₉ClN₄O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 310.78

Ref: TM-T15760