CAS 107444-51-9

glucagon-like peptide I fragment 7-36*amide human

Description:

Glucagon-like peptide-1 (GLP-1) fragment 7-36 amide is a peptide hormone that plays a crucial role in glucose metabolism and appetite regulation. It is derived from the proglucagon gene and is primarily secreted by the intestinal L-cells in response to food intake. This peptide consists of 30 amino acids and is known for its ability to stimulate insulin secretion in a glucose-dependent manner, thereby helping to lower blood sugar levels. Additionally, GLP-1 fragment 7-36 amide inhibits glucagon release, slows gastric emptying, and promotes satiety, making it a target for diabetes treatment and obesity management. The amide form indicates that the C-terminus of the peptide is amidated, which is important for its biological activity and stability. Due to its physiological effects, GLP-1 and its analogs are utilized in therapeutic applications, particularly in the management of type 2 diabetes mellitus. The CAS number 107444-51-9 uniquely identifies this specific peptide in chemical databases, facilitating research and development in pharmacology and biochemistry.

Formula: C₁₄₉H₂₂₆N₄₀O₄₅

Synonyms:

• Glucagon-Like Peptide 1 (7-36) amide (human)
• H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2
• Glp-1(7-36)
• Glucagon-Like Peptide I Fragment 7-36 Amide Human

Glucagon-Like Peptide-1 (7-36) amide, human

CAS: 107444-51-9

For cellular and molecular biology applications

Formula: C₁₄₉H₂₂₆N₄₀O₄₅

Color and Shape: Lyophilized Powder, White

Molecular weight: 3297.7

Ref: 02-J66197

GLP-1 (7-36) amide (human, bovine, guinea pig, mouse, rat)

CAS: 107444-51-9

GLP-1 (7-36) amide is secreted from the lower small intestine and shows a strong insulinotropic effect. GLP-1 (7-36) amide is considered as the most important incretin hormone. Its action is mediated by receptors expressed by the endocrine pancreatic B-cells. Considerable interest has focused on the development of this peptide as a therapeutic strategy for non-insulin-dependent (type 2 ) diabetes mellitus and associated neuropathy.

Formula: C₁₄₉H₂₂₆N₄₀O₄₅

Purity: > 96%

Color and Shape: White

Molecular weight: 3297.68

Ref: 01-4030663

GLUCAGON-LIKE PEPTIDE I FRAGMENT 7-36 AMIDE HUMAN

CAS: 107444-51-9

Formula: C₁₄₉H₂₂₆N₄₀O₄₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 3297.6297

Ref: IN-DA008R5L

GLP-1(7-36)

CAS: 107444-51-9

Formula: C₁₄₉H₂₂₆N₄₀O₄₅

Purity: 95%~99%

Color and Shape: White to Off-white Powder

Molecular weight: 3297.63

Ref: BP-BPPG034

GLP-1(7-36), amide

CAS: 107444-51-9

GLP-1 secretion by human enteroendocrine NCI-H716 cells is augmented in a dose-dependent manner by the addition of CPE.Cost-effective and quality-assured.

Formula: C₁₄₉H₂₂₆N₄₀O₄₅

Purity: 99.85%

Color and Shape: White Powder

Molecular weight: 3297.63

Ref: TM-T3984

GLP-1 (7-36) amide

CAS: 107444-51-9

This is an incretin hormone that causes glucose dependent release of insulin by pancreatic beta cells. It is the cleavage product of GLP-1 (1-36) amide peptide.  This peptide, human GLP-1 (7–36), shares the same sequence with preproglucagon (78-107), amide, human.

Formula: C₁₄₉H₂₂₆N₄₀O₄₅

Color and Shape: Powder

Molecular weight: 3,297.63 g/mol

Ref: 3D-CRB1000250

Glucagon-like Peptide 1 (Human, 7-36 Amide)

CAS: 107444-51-9

Glucagon-like peptide 1 (GLP-1) is a peptide hormone that belongs to the glucagon family. It is a 36 amino acid polypeptide and is naturally synthesized in the ileum of humans, pigs, and cows. GLP-1 is an activator of ion channels, which are protein structures that regulate the flow of ions across cell membranes. This hormone also has been shown to inhibit the activity of protein interactions at the cell membrane or ligand binding to receptors.

Formula: C₁₄₉H₂₂₆N₄₀O₄₅

Purity: Min. 95%

Molecular weight: 3,297.6 g/mol

Ref: 3D-PGL-4344-V

Glucagon-Like Peptide I (7-36), amide, human

CAS: 107444-51-9

Custom research peptide; min purity 95%.

Formula: C₁₄₉H₂₂₉N₄₀O₄₅

Purity: Min. 95%

Molecular weight: 3,297.7 g/mol

Ref: 3D-PG16978

Glucagon-Like Peptide I (7-36), amide, human

CAS: 107444-51-9

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

Formula: C₁₄₉H₂₂₆N₄₀O₄₅

Molecular weight: 3,297.7 g/mol

Ref: 3D-PP50623

Glucagon-like peptide 1 (7-36) amide

CAS: 107444-51-9

Glucagon-like peptide 1 (7-36) amide is a peptide hormone produced by the ileum and colon of the small intestine in response to food intake. It stimulates insulin release from the pancreas, inhibits glucagon secretion, and slows gastric emptying. GLP-1 is also a potent regulator of glucose homeostasis. The GLP-1 analogues are used for treatment of type 2 diabetes mellitus. These analogues are either injected or taken orally and mimic the effect of natural GLP-1 on blood sugar regulation and appetite control. The long duration of action means that daily injections or multiple oral doses are required to maintain therapeutic levels.

Formula: C₁₄₉H₂₂₆N₄₀O₄₅

Purity: Min. 95%

Molecular weight: 3,297.63 g/mol

Ref: 3D-FG109975