CAS 1075236-89-3

(2R)-2-[[4-[[(3,4-Dihydro-2H-pyrano[2,3-c]pyridin-6-yl)methyl]amino]-1-piperidinyl]methyl]-1,2-dihydro-3H,8H-2a,5,8a-triazaacenaphthylene-3,8-dione

Description:

The chemical substance with the name "(2R)-2-[[4-[[(3,4-Dihydro-2H-pyrano[2,3-c]pyridin-6-yl)methyl]amino]-1-piperidinyl]methyl]-1,2-dihydro-3H,8H-2a,5,8a-triazaacenaphthylene-3,8-dione" and CAS number "1075236-89-3" is a complex organic compound characterized by its multi-cyclic structure and the presence of various functional groups, including amines and diketones. The compound features a tricyclic core, which contributes to its potential biological activity. Its stereochemistry is indicated by the (2R) designation, suggesting specific spatial arrangements of atoms that may influence its interaction with biological targets. The presence of a piperidine ring and a pyrano-pyridine moiety suggests potential pharmacological properties, possibly related to neuroactivity or other therapeutic effects. The compound's solubility, stability, and reactivity would depend on its specific functional groups and overall molecular structure, making it a candidate for further investigation in medicinal chemistry and drug development.

Formula: C₂₄H₂₈N₆O₃

InChI: InChI=1S/C24H28N6O3/c31-22-4-3-20-24-29(22)15-19(30(24)23(32)13-27-20)14-28-7-5-17(6-8-28)25-11-18-10-16-2-1-9-33-21(16)12-26-18/h3-4,10,12-13,17,19,25H,1-2,5-9,11,14-15H2/t19-/m1/s1

InChI key: InChIKey=PZFAZQUREQIODZ-LJQANCHMSA-N

SMILES: C([C@H]1N2C=3N(C1)C(=O)C=CC3N=CC2=O)N4CCC(NCC=5C=C6C(=CN5)OCCC6)CC4

Synonyms:

• (2R)-2-[[4-[[(3,4-Dihydro-2H-pyrano[2,3-c]pyridin-6-yl)methyl]amino]-1-piperidinyl]methyl]-1,2-dihydro-3H,8H-2a,5,8a-triazaacenaphthylene-3,8-dione
• 3H,8H-2a,5,8a-Triazaacenaphthylene-3,8-dione, 2-[[4-[[(3,4-dihydro-2H-pyrano[2,3-c]pyridin-6-yl)methyl]amino]-1-piperidinyl]methyl]-1,2-dihydro-, (2R)-
• GSK 2140944
• (R)-2-((4-(((3,4-Dihydro-2H-pyrano[2,3-c]pyridin-6-yl)methyl)amino)piperidin-1-yl)methyl)-1,2-dihydro-2a,5,8a-triazaacenaphthylene-3,8-dione
• Gepotidacin

(R)-2-((4-(((3,4-Dihydro-2H-pyrano[2,3-c]pyridin-6-yl)methyl)amino)piperidin-1-yl)methyl)-1,2-dihydro-3H,8H-2a,5,8a-triazaacenaphthylene-3,8-dione

CAS: 1075236-89-3

(R)-2-((4-(((3,4-Dihydro-2H-pyrano[2,3-c]pyridin-6-yl)methyl)amino)piperidin-1-yl)methyl)-1,2-dihydro-3H,8H-2a,5,8a-triazaacenaphthylene-3,8-dione

Purity: 99%

Molecular weight: 448.53g/mol

Ref: 54-OR1074625

Gepotidacin

CAS: 1075236-89-3

Gepotidacin is a triazaacenaphthylene antibacterial inhibiting bacterial type II topoisomerase with lower resistance potential than fluoroquinolones.

Formula: C₂₄H₂₈N₆O₃

Purity: 99.88%

Color and Shape: Solid

Molecular weight: 448.52

Ref: TM-T11391L

Gepotidacin

CAS: 1075236-89-3

Gepotidacin is a water-soluble and biocompatible polymer. It is used as an antimicrobial agent in wastewater treatment. Gepotidacin binds to the bacterial DNA gyrase and prevents the unwinding of the double helix, inhibiting DNA replication. Gepotidacin has been shown to inhibit the growth of wild-type strains of bacteria, such as Staphylococcus aureus, but not resistant mutants. In vitro studies have shown that gepotidacin inhibits Toll-like receptor (TLR) signaling through inhibition of myeloid differentiation primary response protein-9 (MMP-9) activity.

Formula: C₂₄H₂₈N₆O₃

Purity: Min. 95%

Molecular weight: 448.52 g/mol

Ref: 3D-ATB23689