CAS 107549-26-8

2,6-Difluorobenzylmagnesium bromide

Description:

2,6-Difluorobenzylmagnesium bromide is an organometallic compound that belongs to the class of Grignard reagents, which are characterized by the presence of a carbon-magnesium bond. This compound features a benzyl group substituted with two fluorine atoms at the 2 and 6 positions of the aromatic ring, enhancing its reactivity and influencing its electronic properties. As a Grignard reagent, it is highly reactive, particularly with electrophiles, making it valuable in organic synthesis for forming carbon-carbon bonds. The presence of fluorine atoms can also impart unique characteristics, such as increased lipophilicity and altered reactivity compared to non-fluorinated analogs. 2,6-Difluorobenzylmagnesium bromide is typically handled under anhydrous conditions due to its sensitivity to moisture, which can lead to hydrolysis and the formation of by-products. Its applications include the synthesis of various organic compounds, including pharmaceuticals and agrochemicals, where precise modifications of molecular structures are required. Proper safety precautions should be taken when working with this compound due to its reactivity and potential hazards.

Formula: C₇H₅BrF₂Mg

InChI: InChI=1S/C7H5F2.BrH.Mg/c1-5-6(8)3-2-4-7(5)9;;/h2-4H,1H2;1H;/q;;+1/p-1

InChI key: InChIKey=KEOOIBWMYNKEEF-UHFFFAOYSA-M

SMILES: C([Mg]Br)C1=C(F)C=CC=C1F

Synonyms:

• Bromo[(2,6-difluorophenyl)methyl]magnesium
• Magnesium, bromo[(2,6-difluorophenyl)methyl]-
• Benzene, 1,3-difluoro-2-methyl-, magnesium complex
• 2,6-Difluorobenzylmagnesium bromide
• 2,6-DifluorobenzylMagnesiuM broMide, 0.25M in 2-MeTHF
• 2,6-Difluorobenzylmagnesium bromide, 0.25 M in Ether

2,6-Difluorobenzylmagnesium bromide, 0.25M in 2-MeTHF

CAS: 107549-26-8

2,6-Difluorobenzylmagnesium bromide, 0.25M in 2-MeTHF is used as a pharmaceutical intermediate. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar prod

Formula: C₇H₅BrF₂Mg

Molecular weight: 231.32

Ref: 02-H54189