CAS 1076199-40-0: Quetiapine N-oxide

Description: Quetiapine N-oxide is a chemical compound derived from quetiapine, an atypical antipsychotic medication primarily used to treat schizophrenia and bipolar disorder. As a metabolite of quetiapine, Quetiapine N-oxide exhibits distinct characteristics, including its molecular structure, which features an N-oxide functional group. This modification can influence its pharmacological properties and metabolic pathways. The compound is typically characterized by its solubility in organic solvents and its stability under standard laboratory conditions. Quetiapine N-oxide may also exhibit varying degrees of biological activity compared to its parent compound, potentially affecting its therapeutic efficacy and side effect profile. Research into its specific interactions with neurotransmitter receptors and its role in the overall pharmacokinetics of quetiapine is ongoing, contributing to a better understanding of its implications in clinical settings. As with many metabolites, the study of Quetiapine N-oxide is essential for comprehending the full pharmacological landscape of quetiapine treatment.

Formula: C₂₁H₂₅N₃O₃S

InChI: InChI=1S/C21H25N3O3S/c25-14-16-27-15-13-24(26)11-9-23(10-12-24)21-17-5-1-3-7-19(17)28-20-8-4-2-6-18(20)22-21/h1-8,25H,9-16H2

InChI key: InChIKey=VVBXDYFGQNNTDS-UHFFFAOYSA-N

SMILES: O=N1(CCOCCO)CCN(C2=NC=3C=CC=CC3SC=4C=CC=CC42)CC1

Synonyms:

• Quetiapine N-oxide
• Ethanol, 2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-oxido-1-piperazinyl)ethoxy]-
• 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-oxido-1-piperazinyl)ethoxy]ethanol

Quetiapine Related Compound H (4-(Dibenzo[b,f][1,4]thiazepin-11-yl)-1-[2-(2-hydroxyethoxy)ethyl]piperazine 1-oxide)

CAS: 1076199-40-0

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

• Formula: C₂₁H₂₅N₃O₃S
• Color and Shape: Powder
• Molecular weight: 399.16166

Quetiapine N-Oxide

CAS: 1076199-40-0

• Formula: C₂₁H₂₅N₃O₃S
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 399.5065

Quetiapine EP Impurity H (Quetiapine USP Related Compound H, Quetiapine N-Oxide)

CAS: 1076199-40-0

• Formula: C₂₁H₂₅N₃O₃S
• Color and Shape: White To Off-White Solid
• Molecular weight: 399.51

Quetiapine N-oxide

CAS: 1076199-40-0

• Purity: 97%
• Molecular weight: 399.51

2-[2-[4-(Dibenzo[b,f][1,4]thiazepin-11-yl)-1-oxidopiperazin-1-yl]ethoxy]ethanol (Quetiapine N-Oxide)

CAS: 1076199-40-0

• Formula: C₂₁H₂₅N₃O₃S
• Color and Shape: Neat
• Molecular weight: 399.51

Quetiapine N-Oxide

CAS: 1076199-40-0

Impurity Quetiapine EP Impurity H Stability Hygroscopic Applications Quetiapine N-Oxide (Quetiapine EP Impurity H) is …

• Formula: C₂₁H₂₅N₃O₃S
• Color and Shape: White To Light Brown
• Molecular weight: 399.51

2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol N-oxide

CAS: 1076199-40-0

2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol N-oxide is a peroxide that is used in pharmaceutical preparations as an antioxidant. It …

• Formula: C₂₁H₂₅N₃O₃S
• Purity: Min. 95%
• Color and Shape: Tan to pale orange solid.
• Molecular weight: 399.51 g/mol