CAS 1077-27-6

(S)-Thioctic acid

Description:

(S)-Thioctic acid, also known as alpha-lipoic acid, is a naturally occurring compound that plays a crucial role in mitochondrial bioenergetics and acts as a cofactor for several enzyme complexes involved in energy metabolism. It is characterized by its unique structure, which includes a dithiolane ring and a carboxylic acid group, allowing it to participate in redox reactions. This compound is both water-soluble and fat-soluble, enabling it to function in various biological environments. Thioctic acid is known for its antioxidant properties, helping to neutralize free radicals and regenerate other antioxidants, such as vitamins C and E. Additionally, it has been studied for its potential therapeutic effects in conditions like diabetes, neuropathy, and oxidative stress-related disorders. The (S)-enantiomer is the biologically active form, while the (R)-enantiomer is less active. Its safety profile is generally favorable, with mild side effects reported in some cases. Overall, (S)-Thioctic acid is a significant compound in both biochemistry and potential clinical applications.

Formula: C₈H₁₄O₂S₂

InChI: InChI=1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10)/t7-/m0/s1

InChI key: InChIKey=AGBQKNBQESQNJD-ZETCQYMHSA-N

SMILES: C(CCCC(O)=O)[C@H]1CCSS1

Synonyms:

• (-)-Thioctic acid
• (3S)-1,2-Dithiolane-3-pentanoic acid
• (S)-(-)-Lipoic acid
• (S)-(-)-Thioctic acid
• 1,2-Dithiolane-3-pentanoic acid (3S)-
• 1,2-Dithiolane-3-pentanoic acid, (3S)- (9CI)
• 1,2-Dithiolane-3-pentanoic acid, (S)-
• 5-[(3S)-1,2-dithiolan-3-yl]pentanoic acid
• L-Thioctic Acid
• S- Lipoicacid (L-Lipoic Acid)
• S-(-)-α-Lipoic acid
• S-Lipoic

5-[(3S)-Dithiolan-3-yl]pentanoic acid

CAS: 1077-27-6

Formula: C₈H₁₄O₂S₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 206.3256

Ref: IN-DA008R57

(S)-5-(1,2-Dithiolan-3-yl)pentanoic acid

CAS: 1077-27-6

(S)-5-(1,2-Dithiolan-3-yl)pentanoic acid

Purity: 98%

Molecular weight: 206.33g/mol

Ref: 54-OR95273

S-Thioctic Acid

CAS: 1077-27-6

Formula: C₈H₁₄O₂S₂

Molecular weight: 206.32

Ref: 4Z-T-8835

(S)-(-)-α-Lipoic Acid

Controlled Product

CAS: 1077-27-6

Applications A fat-metabolism stimulator. Antioxidant.
References Plotzker, R., et al.: Am. J. Med. Sci., 283, 79 (1982), Evans, J., et al.: Diabetes Technol. Ther., 2, 401 (2000), Konrad, D., et al.: Diabetes, 50, 1464 (2001), Lockhart, B., et al.: Brain Res., 855, 292 (2000),

Formula: C₈H₁₄O₂S₂

Color and Shape: Light Yellow

Molecular weight: 206.33

Ref: TR-L468730

(S)-(-)-α-Lipoic acid

CAS: 1077-27-6

(S)-(-)-a-Lipoic acid (DLPA) is a reactive, oxidative molecule that has been shown to have antioxidant properties. DLPA is a natural compound found in the human body and is essential for energy metabolism and mitochondrial membrane depolarization. It has been shown to be beneficial in cases of bowel disease and diabetic neuropathy. DLPA has also been shown to be clinically relevant in the treatment of ischemia–reperfusion injury and cisplatin-induced nephrotoxicity, as well as having anti-inflammatory properties. DLPA may also help reduce symptoms of Parkinson's disease and other conditions.

Formula: C₈H₁₄O₂S₂

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 206.33 g/mol

Ref: 3D-FL24905

(S)-5-(1,2-Dithiolan-3-yl)pentanoic acid

CAS: 1077-27-6

Formula: C₈H₁₄O₂S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 206.32

Ref: 10-F091890

S-Thioctic Acid

CAS: 1077-27-6

Formula: C₈H₁₄O₂S₂

Molecular weight: 206.32

Ref: ST-EA-CP-T110001