CAS 1077-93-6

Ternidazole

Description:

Ternidazole is an antifungal and antiparasitic agent belonging to the imidazole class of compounds. It is primarily used in the treatment of various infections, including those caused by protozoa and certain fungi. The chemical structure of ternidazole features a 1H-imidazole ring, which is essential for its biological activity. It is typically administered orally and is known for its effectiveness against infections such as trichomoniasis and giardiasis. Ternidazole exhibits a broad spectrum of activity, making it useful in clinical settings. The compound is generally well-tolerated, although side effects may include gastrointestinal disturbances and allergic reactions in some individuals. Its mechanism of action involves the disruption of nucleic acid synthesis in the target organisms, leading to their death. Ternidazole is also characterized by its solubility in organic solvents, which influences its formulation in pharmaceutical preparations. As with any medication, proper dosage and adherence to treatment guidelines are crucial for maximizing efficacy and minimizing potential adverse effects.

Formula: C₇H₁₁N₃O₃

InChI: InChI=1S/C7H11N3O3/c1-6-8-5-7(10(12)13)9(6)3-2-4-11/h5,11H,2-4H2,1H3

InChI key: InChIKey=DUOHVNSMLSPTMI-UHFFFAOYSA-N

SMILES: C(CCO)N1C(N(=O)=O)=CN=C1C

Synonyms:

• 1-(3-Hydroxypropyl)-2-methyl-5-nitro-1H-imidazole
• 1-(3-Hydroxypropyl)-2-methyl-5-nitroimidazole
• 1H-Imidazole-1-propanol, 2-methyl-5-nitro-
• 2-Methyl-5-nitro-1H-imidazole-1-propanol
• 2-Methyl-5-nitroimidazole-1-propanol
• 3-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-1-ol
• Imidazole-1-propanol, 2-methyl-5-nitro-
• Ternidazol
• Ternidazol [INN-Spanish]
• Ternidazole [INN]
• Ternidazolum
• Ternidazolum [INN-Latin]
• Unii-4N8R018Qb0
• Ternidazole

Ternidazole

CAS: 1077-93-6

Formula: C₇H₁₁N₃O₃

Molecular weight: 185.18

Ref: 4Z-T-173004

2-Methyl-5-nitroimidazole-1-propanol

CAS: 1077-93-6

2-Methyl-5-nitroimidazole-1-propanol (2MI) is a matrix effect correction reagent that can be used to reconstitute the original concentrations of drugs in plasma and urine samples. It is also used for sample preparation, validation and quality control. 2MI has been shown to bind with cervical cancer cells, which may be due to its ability to bind with drug receptors on the surface of these cells. A liquid chromatography-mass spectrometry (LC-MS/MS) method was developed to measure 2MI in plasma and urine samples. The method was validated using test samples and showed good agreement with the target concentration.

Formula: C₇H₁₁N₃O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 185.18 g/mol

Ref: 3D-FM76444

2-Methyl-5-nitroimidazole-1-propanol

Controlled Product

CAS: 1077-93-6

Formula: C₇H₁₁N₃O₃

Color and Shape: Neat

Molecular weight: 185.18

Ref: TR-M240400