CAS 107736-98-1

Umespirone

Description:

Umespirone is a chemical compound classified as an anxiolytic agent, primarily used in the treatment of anxiety disorders. It is a member of the azapirone class, which is characterized by its unique structure that includes a piperazine ring. Umespirone acts as a partial agonist at serotonin receptors, particularly the 5-HT1A subtype, which contributes to its anxiolytic effects. The compound is known for its relatively favorable side effect profile compared to traditional benzodiazepines, making it a potential alternative for patients seeking anxiety relief without the risk of dependence. In addition to its anxiolytic properties, Umespirone may also exhibit effects on dopaminergic systems, which could influence mood and behavior. Its pharmacokinetics, including absorption, distribution, metabolism, and excretion, are important for determining its therapeutic efficacy and safety. Overall, Umespirone represents a significant advancement in the pharmacological management of anxiety, with ongoing research exploring its full therapeutic potential and mechanisms of action.

Formula: C₂₈H₄₀N₄O₅

InChI: InChI=1S/C28H40N4O5/c1-5-6-14-31-24(33)22-26(35)32(27(36)23(25(31)34)28(22,2)3)15-10-9-13-29-16-18-30(19-17-29)20-11-7-8-12-21(20)37-4/h7-8,11-12,22-23H,5-6,9-10,13-19H2,1-4H3

InChI key: InChIKey=BXNRTMZZILHVNJ-UHFFFAOYSA-N

SMILES: CC1(C)C2C(=O)N(CCCCN3CCN(CC3)C4=C(OC)C=CC=C4)C(=O)C1C(=O)N(CCCC)C2=O

Synonyms:

• KC 9172
• N-Butyl-N'-(4-(4-(o-methoxyphenyl)-1-piperazinyl)butyl)-2,2-dimethyl-1,1,3,3-propanetetracarboxylic 1,3:1,3-diimide
• Umespirona
• 3-butyl-7-{4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl}-9,9-dimethyl-3,7-diazabicyclo[3.3.1]nonane-2,4,6,8-tetrone
• KC 9172
• Umespirone [INN]
• 3-Butyl-7-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]-9,9-dimethyl-3,7-diazabicyclo[3.3.1]nonane-2,4,6,8-tetrone
• Umespirone
• Umespironum [INN-Latin]
• Umespirona [INN-Spanish]
• 3,7-Diazabicyclo(3.3.1)nonane-2,4,6,8-tetrone, 3-butyl-7-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)-9,9-dimethyl-
• Umespironum
• 3,7-Diazabicyclo[3.3.1]nonane-2,4,6,8-tetrone, 3-butyl-7-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]-9,9-dimethyl-

Umespirone

CAS: 107736-98-1

Umespirone is a potential antipsychotic/anxiolytic drug of the azapirone class. It possesses anxiolytic and antipsychotic properties.

Formula: C₂₈H₄₀N₄O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 512.64

Ref: TM-T24923