CAS 107745-56-2
:aldgamycin G
Description:
Aldgamycin G, with the CAS number 107745-56-2, is a member of the aminoglycoside class of antibiotics, which are known for their effectiveness against a variety of bacterial infections. This compound exhibits a complex structure characterized by multiple sugar moieties and an amino group, which contribute to its biological activity. Aldgamycin G is primarily produced by certain strains of Streptomyces bacteria and functions by inhibiting bacterial protein synthesis, thereby exerting its antimicrobial effects. It is particularly noted for its activity against Gram-negative bacteria. The substance is typically administered in a clinical setting, often in combination with other antibiotics to enhance efficacy and reduce the potential for resistance. Its pharmacokinetics, including absorption, distribution, metabolism, and excretion, are critical for determining appropriate dosing regimens. As with many aminoglycosides, potential side effects may include nephrotoxicity and ototoxicity, necessitating careful monitoring during treatment. Overall, Aldgamycin G represents an important tool in the arsenal against bacterial infections, particularly in cases where resistance to other antibiotics is a concern.
Formula:C37H56O15
InChI:InChI=1/C37H56O15/c1-17-10-13-27(39)47-21(5)24(16-45-34-32(44-9)31(43-8)28(40)22(6)48-34)30-26(50-30)12-11-25(38)18(2)14-19(3)29(17)51-35-33(41)37(15-20(4)46-35)23(7)49-36(42)52-37/h10-13,17-24,26,28-35,40-41H,14-16H2,1-9H3/b12-11+,13-10+/t17-,18+,19-,20+,21+,22+,23-,24+,26-,28+,29+,30+,31+,32+,33-,34+,35-,37?/m0/s1
Synonyms:- 8-Deoxyaldgamycin F
- Aldgamycin F, 8-deoxy-
- Aldgamycin G
- [(1R,2R,3R,6E,8S,9S,10S,12R,14E,16S)-9-{[(4S,6R,7S,9R)-6-hydroxy-4,9-dimethyl-2-oxo-1,3,8-trioxaspiro[4.5]dec-7-yl]oxy}-3,8,10,12-tetramethyl-5,13-dioxo-4,17-dioxabicyclo[14.1.0]heptadeca-6,14-dien-2-yl]methyl 6-deoxy-2,3-di-O-methyl-beta-D-allopyranoside
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Aldgamycin G
CAS:<p>Aldgamycin G is a Macrolide antibiotic against Gram-positive bacteria isolated from Streptomyces avidinii.</p>Formula:C37H56O15Color and Shape:SolidMolecular weight:740.83
