CAS 107753-78-6

Zafirlukast

Description:

Zafirlukast is a leukotriene receptor antagonist primarily used in the management of asthma and allergic rhinitis. It functions by inhibiting the action of leukotrienes, which are inflammatory mediators that contribute to bronchoconstriction and airway inflammation. The chemical formula of Zafirlukast is C18H21N3O2S, and it has a molecular weight of approximately 345.45 g/mol. This compound is typically administered orally and is known for its relatively high bioavailability. Zafirlukast is characterized by its ability to reduce the frequency of asthma attacks and improve lung function, making it a valuable therapeutic option for patients with chronic respiratory conditions. It is important to note that Zafirlukast may interact with other medications and can have side effects, including liver enzyme elevations and gastrointestinal disturbances. As with any medication, it is essential for patients to consult healthcare professionals for personalized advice and monitoring during treatment.

Formula: C₃₁H₃₃N₃O₆S

InChI: InChI=1S/C31H33N3O6S/c1-20-8-4-7-11-29(20)41(37,38)33-30(35)22-13-12-21(28(17-22)39-3)16-23-19-34(2)27-15-14-24(18-26(23)27)32-31(36)40-25-9-5-6-10-25/h4,7-8,11-15,17-19,25H,5-6,9-10,16H2,1-3H3,(H,32,36)(H,33,35)

InChI key: InChIKey=YEEZWCHGZNKEEK-UHFFFAOYSA-N

SMILES: C(C=1C=2C(N(C)C1)=CC=C(NC(OC3CCCC3)=O)C2)C4=C(OC)C=C(C(NS(=O)(=O)C5=C(C)C=CC=C5)=O)C=C4

Synonyms:

• Carbamic acid, [3-[[2-methoxy-4-[[[(2-methylphenyl)sulfonyl]amino]carbonyl]phenyl]methyl]-1-methyl-1H-indol-5-yl]-, cyclopentyl ester
• Carbamic acid, N-[3-[[2-methoxy-4-[[[(2-methylphenyl)sulfonyl]amino]carbonyl]phenyl]methyl]-1-methyl-1H-indol-5-yl]-, cyclopentyl ester
• Cyclopentyl 3-[2-methoxy-4-[(o-tolylsulfonyl)carbamoyl]benzyl]-1-methylindole-5-carbamate
• Cyclopentyl N-[3-{[2-methoxy-4-[(2-methylphenyl) sulfonylcarbamoyl]phenyl]methyl}-1-methyl-indol-5-yl]carbamate
• Cyclopentyl [3-[[2-methoxy-4-[(2-methylphenyl)sulfonylcarbamoyl]phenyl]methyl]-1-methyl-indol-5-yl]aminoformate
• ICI 204219
• Zafirlukast
• cyclopentyl [3-(2-methoxy-4-{[(2-methylphenyl)sulfonyl]carbamoyl}benzyl)-1-methyl-1H-indol-5-yl]carbamate

Zafirlukast

CAS: 107753-78-6

Formula: C₃₁H₃₃N₃O₆S

Purity: >98.0%(HPLC)

Color and Shape: White to Gray to Brown powder to crystaline

Molecular weight: 575.68

Ref: 3B-Z0029

Zafirlukast

CAS: 107753-78-6

Formula: C₃₁H₃₃N₃O₆S

Purity: 99%

Color and Shape: Solid

Molecular weight: 575.6752

Ref: IN-DA007DU5

Zafirlukast

CAS: 107753-78-6

Zafirlukast

Purity: 99%

Molecular weight: 575.68g/mol

Ref: 54-OR1025471

Zafirlukast

CAS: 107753-78-6

Formula: C₃₁H₃₃N₃O₆S

Color and Shape: Pale Pink Solid

Molecular weight: 575.69

Ref: 4Z-Z-121

Zafirlukast

CAS: 107753-78-6

Zafirlukast

Purity: ≥98%

Molecular weight: 575.68g/mol

Ref: 54-BUP11775

Zafirlukast-13C-d6

CAS: 107753-78-6

Formula: C₃₀₁₃CH₂₇D₆N₃O₆S

Color and Shape: Off-White Solid

Molecular weight: 582.71

Ref: 4Z-Z-127

Zafirlukast-13C-d3

CAS: 107753-78-6

Formula: C₃₀₁₃CH₃₀D₃N₃O₆S

Color and Shape: Off-White Solid

Molecular weight: 579.69

Ref: 4Z-Z-123

Zafirlukast

CAS: 107753-78-6

Formula: C₃₁H₃₃N₃O₆S

Purity: ≥ 98.5%

Color and Shape: Off-white to pink or light yellow/brown powder

Molecular weight: 575.68

Ref: 7W-GP6218

Zafirlukast Impurity 4

CAS: 107753-78-6

Formula: C₃₁H₃₂ClN₃O₆S

Color and Shape: Pale Pink Solid

Molecular weight: 610.12

Ref: 4Z-Z-1211

Zafirlukast

CAS: 107753-78-6

Zafirlukast (ICI 204219) is an orally leukotriene D4 receptor (LTD4) antagonist. Zafirlukast has anti-asthmatic and anti-inflammatory effects. Cost-effective and quality-assured.

Formula: C₃₁H₃₃N₃O₆S

Purity: 99% - 99.83%

Color and Shape: Solid

Molecular weight: 575.68

Ref: TM-T6736

Zafirlukast-d7

CAS: 107753-78-6

Formula: C₃₁H₂₆D₇N₃O₆S

Molecular weight: 582.73

Ref: 4Z-Z-122

Zafirlukast

Controlled Product

CAS: 107753-78-6

Applications A potent, selective and orally active cysteinyl leukotriene type 1 receptor antagonist. Used as an antiasthmatic.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Matassa, V.G., et al.: J. Med. Chem., 33, 1781 (1990), Findlay, S.R., et al.: J. Allergy Clin. Immunol., 89, 1040 (1992), Krell, R.D., et al.: Am. Rev. Respir. Dis., 141, 978 (1990), Dunn, C.J., Drugs, 61, 285 (2001),

Formula: C₃₁H₃₃N₃O₆S

Color and Shape: Pink Light Orange

Molecular weight: 575.68

Ref: TR-Z125000

Zafirlukast

CAS: 107753-78-6

Purity: 95%

Color and Shape: Solid

Molecular weight: 575.679992675781

Ref: 10-F093405

Zafirlukast

CAS: 107753-78-6

Cysteinyl leukotriene receptor antagonist

Formula: C₃₁H₃₃N₃O₆S

Purity: Min. 98 Area-%

Color and Shape: Off-White Powder

Molecular weight: 575.68 g/mol

Ref: 3D-FZ28747

Zafirlukast - Bio-X ™

CAS: 107753-78-6

Zafirlukast is a leukotriene receptor antagonist that is used for the chronic treatment of asthma and prophylaxis. This drug inhibits the action of cysteinyl leukotrienes on the CysLT1 receptors and as a result, it reduces constriction of the airways and reduces inflammation of the breathing passages.

Formula: C₃₁H₃₃N₃O₆S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 575.68 g/mol

Ref: 3D-BZ164562