CAS 107754-14-3

4-(5-Amino-1-methyl-1H-indol-3-ylmethyl)-3-methoxy-benzoic acid methyl ester

Description:

4-(5-Amino-1-methyl-1H-indol-3-ylmethyl)-3-methoxy-benzoic acid methyl ester, with CAS number 107754-14-3, is a chemical compound characterized by its complex structure, which includes an indole moiety and a methoxy-substituted benzoic acid derivative. This compound features an amino group, which contributes to its potential biological activity, and a methyl ester functional group that can influence its solubility and reactivity. The presence of the indole ring suggests potential interactions with biological systems, as indole derivatives are known for their roles in pharmaceuticals and natural products. The methoxy group enhances the compound's lipophilicity, potentially affecting its pharmacokinetic properties. Overall, this compound may exhibit interesting chemical behavior and biological activity, making it a subject of interest in medicinal chemistry and drug development. However, specific applications and effects would depend on further empirical studies and context within biological systems.

Formula: C₁₉H₂₀N₂O₃

Synonyms:

• 3-Methoxy-4-(1-Methyl-5-Aminoindol-3-Ylmethyl)Benzoate
• 4-(5-Amino-1-methyl-1H-indol-3-ylmethyl)-3-methoxy-benzoic a...
• Zafirlukast 5-Aminoindole Impurity
• Methyl 4-[(5-aMino-1-Methyl-1H-indol-3-yl)Methyl]-3-Methoxybenzoate
• methyl 4-[(5-amino-1-methylindol-3-yl)methyl]-3-methoxybenzoate
• 4-(5-Amino-1-methyl-1H-indol-3-ylmethyl)-3-methoxy-benzoic acid methyl ester
• Methyol 4-(5-Amino-1-Methyl Indol-3-yl Methyl)-3-Methoxy Benzoate
• Benzoic acid, 4-[(5-aMino-1-Methyl-1H-indol-3-yl)Methyl]-3-Methoxy-, Methyl ester

Methyl 4-[(5-Amino-1-methylindol-3-yl)methyl]-3-methoxybenzoate

CAS: 107754-14-3

Formula: C₁₉H₂₀N₂O₃

Color and Shape: Liquid

Molecular weight: 324.3737

Ref: IN-DA007DU4

Methyl 4-[(5-Amino-1-methylindol-3-yl)methyl]-3-methoxybenzoate

CAS: 107754-14-3

Applications Methyl 4-[(5-Amino-1-methylindol-3-yl)methyl]-3-methoxybenzoate is an intermediate used in the preparation of Zafirlukast (Z125000), a potent, selective and orally active cysteinyl leukotriene type 1 receptor antagonist.
References Matassa, V.G., et al.: J. Med. Chem., 33, 1781 (1990); Findlay, S.R., et al.: J. Allergy Clin. Immunol., 89, 1040 (1992); Krell, R.D., et al.: Am. Rev. Respir. Dis., 141, 978 (1990); Dunn, C.J., Drugs, 61, 285 (2001); Goverdhan, G., et al.: J. Pharma. Biomed. Anal., 49, 895 (2009)

Formula: C₁₉H₂₀N₂O₃

Color and Shape: Neat

Molecular weight: 324.37

Ref: TR-M258650

Methyl 4-[(5-amino-1-methylindol-3-yl)methyl]-3-methoxybenzoate

CAS: 107754-14-3

Methyl 4-[(5-amino-1-methylindol-3-yl)methyl]-3-methoxybenzoate is a metabolite of the drug methyl 3-[(5-amino-1-methylindol-3-yl)methyl]benzoate. It is a white solid that is soluble in alcohol, acetone, and chloroform. Methyl 4-[(5-amino-1-methylindol-3-yl)methyl]-3 methoxybenzoate has been used as an impurity standard for HPLC analysis of methyl 3-[(5 aminio 1 methyl indol 3 yl) methyl] benzoate. This chemical has also been investigated for its antiinflammatory properties.

Formula: C₁₉H₂₀N₂O₃

Purity: Min. 95%

Molecular weight: 324.4 g/mol

Ref: 3D-HEA75414

Zafirlukast Impurity 3

CAS: 107754-14-3

Formula: C₁₉H₂₀N₂O₃

Molecular weight: 324.38

Ref: ST-EA-CP-Z7003