CAS 107807-25-0

epelmycin A

Description:

Epelmycin A, with the CAS number 107807-25-0, is a natural product belonging to the class of macrolide antibiotics. It is derived from the fermentation of specific strains of Streptomyces bacteria. Epelmycin A exhibits potent antibacterial activity, particularly against Gram-positive bacteria, making it a subject of interest in medicinal chemistry and pharmaceutical research. Its structure features a large lactone ring, which is characteristic of macrolides, and it may contain various functional groups that contribute to its biological activity. The compound has been studied for its potential applications in treating infections and may also exhibit antitumor properties. As with many antibiotics, the mechanism of action typically involves inhibition of protein synthesis in bacterial cells. However, the specific details of its pharmacokinetics, toxicity, and resistance profiles are still under investigation. Overall, Epelmycin A represents a promising candidate for further research in the development of new antimicrobial agents.

Formula: C₄₂H₅₃NO₁₅

InChI: InChI=1/C42H53NO15/c1-8-42(51)17-26(31-32(35(42)41(50)52-7)39(49)33-34(38(31)48)37(47)30-21(36(33)46)10-9-11-24(30)45)57-29-16-22(43(5)6)40(20(4)55-29)58-28-15-13-25(19(3)54-28)56-27-14-12-23(44)18(2)53-27/h9-11,18-20,22,25-29,35,40,45,48-49,51H,8,12-17H2,1-7H3

Synonyms:

• 1-Naphthacenecarboxylic acid, 2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7,12-tetrahydroxy-6,11-dioxo-4-((2,3,6-trideoxy-3-(dimethylamino)-4-O-((2S-(2alpha,5beta(2S*,6R*),6beta))-tetrahydro-6-methyl-5-((tetrahydro-6-methyl-5-oxo-2H-pyran-2-yl)oxy)-2H-pyran-2-yl)-alpha-L-lyxo-hexopyranosyl)oxy)-, methyl ester
• 1-Naphthacenecarboxylic acid, 2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7,12-tetrahydroxy-6,11-dioxo-4-[[2,3,6-trideoxy-3-(dimethylamino)-4-O-[(2S,5S,6S)-tetrahydro-6-methyl-5-[[(2R,6S)-tetrahydro-6-methyl-5-oxo-2H-pyran-2-yl]oxy]-2H-pyran-2-yl]-α-L-lyxo-hexopyranosyl]oxy]-, methyl ester (9CI)
• Epelmycin A
• methyl 2-ethyl-2,5,7,12-tetrahydroxy-6,11-dioxo-4-{[2,3,6-trideoxy-3-(dimethylamino)-4-O-{6-methyl-5-[(6-methyl-5-oxotetrahydro-2H-pyran-2-yl)oxy]tetrahydro-2H-pyran-2-yl}hexopyranosyl]oxy}-1,2,3,4,6,11-hexahydrotetracene-1-carboxylate
• epelmycin A

Epelmycin A

CAS: 107807-25-0

Epelmycin A exhibits activity against both Gram-positive and Gram-negative bacteria, Candida albicans, and also demonstrates efficacy against leukemia L1210.

Formula: C₄₂H₅₃NO₁₅

Color and Shape: Solid

Molecular weight: 811.868

Ref: TM-TN9981