CAS 107814-37-9

cis-4-[(2-amino-3,5-dibromobenzyl)amino]Cyclohexanol

Description:

Cis-4-[(2-amino-3,5-dibromobenzyl)amino]cyclohexanol is a chemical compound characterized by its unique structural features, including a cyclohexanol ring and an amino group substituted with a dibromobenzyl moiety. The presence of the cis configuration indicates that specific substituents on the cyclohexanol are oriented on the same side of the ring, which can influence the compound's spatial arrangement and reactivity. The dibromobenzyl group contributes to the compound's hydrophobic characteristics and may enhance its biological activity. This compound is of interest in medicinal chemistry due to its potential applications in drug development, particularly in targeting specific biological pathways. Its molecular interactions, solubility, and stability are influenced by the functional groups present, making it a candidate for further research in pharmacology and organic synthesis. As with many organic compounds, safety and handling precautions should be observed, given the presence of bromine, which can pose environmental and health risks.

cis-4-((2-Amino-3,5-dibromobenzyl)amino)cyclohexanol

CAS: 107814-37-9

Formula: C₁₃H₁₈Br₂N₂O

Purity: 95%

Color and Shape: Solid

Molecular weight: 378.1028

Ref: IN-DA008X2V

cis-Ambroxol Hydrochloride

CAS: 107814-37-9

Stability Hygroscopic
Applications cis-Ambroxol Hydrochloride is a cis isomer of Ambroxol Hydrochloride (A575900 ), a metabolite of Bromohexine. Ambroxol Hydrochloride is a bronchosecretolytic drug.
References Jauch, R., et al.: Arzneim-Forsch., 13, 474 (1963)

Formula: C₁₃H₁₈Br₂N₂O·x(HCl)

Color and Shape: Neat

Molecular weight: 378.10 + x(36.46)

Ref: TR-A576147

rac-cis-Ambroxol

Controlled Product

CAS: 107814-37-9

Impurity Ambroxol EP Impurity D
Applications cis-Ambroxol is the cis-isomeric impurity of Ambroxol (A575905). cis-Ambroxol is a metabolite Bromhexine (B678600). Ambroxol EP Impurity D
References Liu, J. et al.: J. Pharmac. Biomed. Anal., 51, 1134 (2010); Schmid, J.: J. Chrom. Biomed. Appl., 414, 65 (1987);

Formula: C₁₃H₁₈Br₂N₂O

Color and Shape: Neat

Molecular weight: 378.10

Ref: TR-A575905

Ambroxol hydrochloride impurity D

CAS: 107814-37-9

Ambroxol hydrochloride impurity D is a diammonium salt with the molecular formula (C6H14N2)2NH4. It has a detection time of 2 minutes and a sensitivity of 0.1 ppm. Chromatographic detection can be used to screen for this impurity in valsartan, which is a drug used to treat high blood pressure. The chromatographic method uses a liquid column with a UV-detection wavelength of 210 nm and an injection volume of 10 μL. The detection method is based on the headspace technique, which involves collecting volatile components from the sample headspace using gas chromatography with flame ionization detection. The hydrogen phosphate ions in the sample react with phosphoric acid to produce hydrogen phosphate and water vapors, which are then measured as an indication of impurities.

Purity: Min. 95%

Ref: 3D-IA63605

cis-4-[[(2-Amino-3,5-dibromophenyl)methyl]amino]cyclohexanol

CAS: 107814-37-9

Cis-4-[[(2-Amino-3,5-dibromophenyl)methyl]amino]cyclohexanol (cis-DBCL) is a drug that has been shown to be effective in the treatment of lung diseases. It has been shown to improve lung function and reduce the amount of lung damage caused by surfactant deficiency in rats. Cis-DBCL also improves endothelial function and reduces inflammation in mice with chronic pulmonary fibrosis. The antiinflammatory effect of cis-DBCL is due to its ability to inhibit the production of prostaglandin E2 and nitric oxide.

Formula: C₁₃H₁₈Br₂N₂O

Purity: Min. 95%

Molecular weight: 378.1 g/mol

Ref: 3D-IA156916