CAS 107910-75-8

Ganciclovir sodium

Description:

Ganciclovir sodium is an antiviral medication primarily used to treat cytomegalovirus (CMV) infections, particularly in immunocompromised patients, such as those with HIV/AIDS or organ transplant recipients. It is a sodium salt form of ganciclovir, which is a synthetic analogue of guanosine. The compound exhibits characteristics such as being a white to off-white crystalline powder, soluble in water, and having a relatively high melting point. Ganciclovir sodium works by inhibiting viral DNA synthesis, thereby preventing the replication of the virus. Its mechanism of action involves selective phosphorylation by viral kinases, leading to the incorporation of the drug into viral DNA, which ultimately disrupts viral replication. The substance is typically administered intravenously or orally, depending on the clinical scenario. Due to its potential side effects, including bone marrow suppression and nephrotoxicity, careful monitoring is required during treatment. Additionally, it is classified as a hazardous substance, necessitating appropriate handling and disposal procedures in clinical settings.

Formula: C₉H₁₃N₅O₄·Na

InChI: InChI=1S/C9H13N5O4.Na/c10-9-12-7-6(8(17)13-9)11-3-14(7)4-18-5(1-15)2-16;/h3,5,15-16H,1-2,4H2,(H3,10,12,13,17);

InChI key: InChIKey=CYNKKJBOBVXOGX-UHFFFAOYSA-N

SMILES: C(OC(CO)CO)N1C2=C(N=C1)C(=O)N=C(N)N2.[Na]

Synonyms:

• 2-Amino-1,9-Dihydro-9-[[2-Hydroxy-1-(Hydroxymethyl)Ethoxy]Methyl]-6H-Purin-6-One Sodium Salt
• 2-amino-9-{[(1,3-dihydroxypropan-2-yl)oxy]methyl}-3,9-dihydro-6H-purin-6-one
• 6H-Purin-6-one, 2-amino-1,9-dihydro-9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-, monosodium salt
• 6H-Purin-6-one, 2-amino-1,9-dihydro-9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-, sodium salt (1:1)
• Cymevene
• Cytovene
• Cytovene IV
• RS 21592 sodium
• sodium 2-amino-9-{[(1,3-dihydroxypropan-2-yl)oxy]methyl}-6,9-dihydro-3H-purin-6-olate
• Ganciclovir sodium

Ganciclovir Sodium Salt

CAS: 107910-75-8

Formula: C₉H₁₂N₅NaO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 277.2124

Ref: IN-DA019FVT

Ganciclovir Sodium Salt

CAS: 107910-75-8

Formula: C₉H₁₂N₅O₄·Na

Color and Shape: White To Off-White Solid

Molecular weight: 254.23 22.99

Ref: 4Z-G-1618

Ganciclovir sodium

CAS: 107910-75-8

Ganciclovir sodium

Purity: ≥98%

Molecular weight: 278.22g/mol

Ref: 54-BUP14935

Ganciclovir sodium

CAS: 107910-75-8

Ganciclovir sodium, a sodium salt with anti-CMV and HSV-1 antiviral properties.

Formula: C₉H₁₃N₅NaO₄

Purity: 99.93%

Color and Shape: Solid

Molecular weight: 278.22

Ref: TM-T22337

Ganciclovir Sodium Salt

Controlled Product

CAS: 107910-75-8

Formula: C₉H₁₂N₅NaO₄

Color and Shape: Neat

Ref: TR-G235050

Ganciclovir sodium

CAS: 107910-75-8

Anti-viral; DNA polymerase inhibitor; dGTP competitive inhibitor

Formula: C₉H₁₃N₅NaO₄

Purity: Min. 95%

Molecular weight: 278.22 g/mol

Ref: 3D-FG40410