CAS 107936-65-2

alpha-gliadin (43-49)

Description:

Alpha-gliadin is a type of prolamin protein primarily found in wheat and is a significant component of gluten. It plays a crucial role in the structure and elasticity of dough, contributing to the texture of baked goods. The designation "43-49" typically refers to a specific range of amino acid sequences or molecular weight characteristics within the alpha-gliadin family. Alpha-gliadin is known for its immunogenic properties, particularly in individuals with celiac disease, where it can trigger an autoimmune response. The CAS number 107936-65-2 specifically identifies this protein, facilitating its recognition in scientific literature and regulatory contexts. In terms of solubility, alpha-gliadin is soluble in alcohol-water mixtures, which is characteristic of prolamins. Its structure includes a high proportion of proline and glutamine residues, contributing to its unique functional properties in food science. Overall, alpha-gliadin is essential for both its nutritional value and its implications in food allergies and intolerances.

Formula: C₄₃H₅₇N₉O₁₁

InChI: InChI=1/C43H57N9O11/c44-28(23-26-12-14-27(53)15-13-26)40(59)50-20-4-9-32(50)37(56)47-29(16-18-35(45)54)41(60)51-21-5-10-33(51)38(57)48-30(17-19-36(46)55)42(61)52-22-6-11-34(52)39(58)49-31(43(62)63)24-25-7-2-1-3-8-25/h1-3,7-8,12-15,28-34,53H,4-6,9-11,16-24,44H2,(H2,45,54)(H2,46,55)(H,47,56)(H,48,57)(H,49,58)(H,62,63)/t28-,29-,30-,31-,32-,33-,34-/m0/s1

SMILES: c1ccc(cc1)C[C@@H](C(=O)O)N=C([C@@H]1CCCN1C(=O)[C@H](CCC(=N)O)N=C([C@@H]1CCCN1C(=O)[C@H](CCC(=N)O)N=C([C@@H]1CCCN1C(=O)[C@H](Cc1ccc(cc1)O)N)O)O)O

Synonyms:

• Gliadophorin (43-49)
• Tyr-pro-gln-pro-gln-pro-phe
• L-Phenylalanine, L-tyrosyl-L-prolyl-L-glutaminyl-L-prolyl-L-glutaminyl-L-prolyl-
• L-tyrosyl-L-prolyl-L-glutaminyl-L-prolyl-L-glutaminyl-L-prolyl-L-phenylalanine
• alpha-Gliadin (43-49)

Gliadorphin-7

CAS: 107936-65-2

Gliadorphin-7, YPQPQPF, is an opioid peptide which is formed during digestion of the gliadin component of the gluten protein. Elevated concentrations of gliadinoorphin-7 due to insufficient proteolysis has been associated with autism, schizophrenia, and celiac disease.

Formula: C₄₃H₅₇N₉O₁₁

Purity: 97.4%

Color and Shape: White Powder

Molecular weight: 875.98

Ref: 01-4057062

α-Gliadin (43-49)

CAS: 107936-65-2

alpha-Gliadin (43-49) is a Gliadian sequence peptide. It could induce leukocyte migration inhibition but be blocked by naloxone.

Formula: C₄₃H₅₇N₉O₁₁

Purity: 98%

Color and Shape: Solid

Molecular weight: 875.97

Ref: TM-T25053

Gliadorphin-7 trifluoroacetate salt

CAS: 107936-65-2

Gliadorphin is a peptide that occurs in cow's milk. It has been shown to be effective against bacterial translocation, which is the passage of bacteria from the gut into other parts of the body. Gliadorphin also has a safety profile, with no observed adverse effects in animal studies and dietary trials. The biological samples used for this study were casein and urine samples. The antibodies used were polyclonal antibodies and Gliadorphin was tested for its ability to bind to bacterial proteins in vivo. Hydration may be necessary for optimal absorption of gliadorphin, as dehydration can affect immune reaction. Gliadorphin does not have any known side effects or drug interactions, but it should not be used by people with an allergy to casein or those who are allergic to mammalian serine proteases (such as trypsin).

Formula: C₄₃H₅₇N₉O₁₁

Purity: Min. 95%

Molecular weight: 875.97 g/mol

Ref: 3D-FG109943