CAS 107952-99-8

(11β)-11,21-Bis(acetyloxy)pregna-4,16-diene-3,20-dione

Description:

(11β)-11,21-Bis(acetyloxy)pregna-4,16-diene-3,20-dione, with CAS number 107952-99-8, is a synthetic steroid compound that belongs to the class of glucocorticoids. This compound features a pregnane backbone, characterized by a steroid structure with multiple fused rings. The presence of acetyloxy groups at the 11 and 21 positions enhances its lipophilicity and biological activity. It exhibits anti-inflammatory and immunosuppressive properties, making it useful in various therapeutic applications, particularly in treating conditions such as asthma, allergies, and autoimmune disorders. The compound's structure includes a diene configuration, which contributes to its reactivity and interaction with biological targets. Its pharmacological effects are mediated through the glucocorticoid receptor, influencing gene expression and cellular responses. As with many steroid derivatives, careful consideration of dosage and potential side effects is essential in clinical use. Overall, this compound exemplifies the complexity and utility of synthetic steroids in medicine.

Formula: C₂₅H₃₂O₆

Synonyms:

• (112)-11,21-Bis(acetyloxy)pregna-4,16-diene-3,20-dione
• Pregna-4,16-diene-3,20-dione, 11,21-bis(acetyloxy)-, (11β)- (9CI)
• (11β)-11,21-Bis(acetyloxy)pregna-4,16-diene-3,20-dione

(11Beta)-11,21-Bis(acetyloxy)pregna-4,16-diene-3,20-dione

Controlled Product

CAS: 107952-99-8

Applications (11β)-11,21-Bis(acetyloxy)pregna-4,16-diene-3,20-dione is an intermediate of Progesterone (P755900), a steroid hormone produced by the corpus luteum. Induces maturation and secretory activity of the uterine endothelium.
References Beyler, R.E., et al.: J. Am. Chem. Soc., 79, 5297 (1957);

Formula: C₂₅H₃₂O₆

Color and Shape: Neat

Molecular weight: 428.52

Ref: TR-B400210