NCG-21, identified by its CAS number 1079821-35-4, is a chemical compound that has garnered attention in various fields, particularly in medicinal chemistry and pharmacology. While specific characteristics such as its molecular formula, structure, and physical properties may not be widely documented, compounds in this category typically exhibit unique biological activities and may serve as potential therapeutic agents. NCG-21 is often studied for its interactions with biological targets, which can include enzymes or receptors, influencing pathways relevant to disease mechanisms. The compound's solubility, stability, and reactivity are essential factors that determine its applicability in research and development. Additionally, safety and toxicity profiles are critical for evaluating its potential use in clinical settings. As with many novel compounds, ongoing research is likely to reveal more about its characteristics, mechanisms of action, and potential applications in drug development. For precise details, consulting specialized databases or scientific literature is recommended.

NCG21 is a GPR120 agonist. NCG21 showed  potent extracellular signal-regulated kinase (ERK) activation in a cloned GPR120 system. NCG21 potently activated ERK, intracellular calcium responses and GLP-1 secretion in murine enteroendocrine STC-1 cells that express GPR120 endogenously. Moreover, administration of NCG21 into the mouse colon caused an increase in plasma GLP-1 levels.

NCG-21

1079821-35-4: NCG-21, identified by its CAS number 1079821-35-4, is a chemical compound that has garnered attention in various fields, particularly in medicinal chemistry and pharmacology. While specific characteristics such as its molecular formula, structure, and physical properties may not be widely documented, compounds in this category typically exhibit unique biological activities and may serve as potential therapeutic agents. NCG-21 is often studied for its interactions with biological targets, which can include enzymes or receptors, influencing pathways relevant to disease mechanisms. The compound's solubility, stability, and reactivity are essential factors that determine its applicability in research and development. Additionally, safety and toxicity profiles are critical for evaluating its potential use in clinical settings. As with many novel compounds, ongoing research is likely to reveal more about its characteristics, mechanisms of action, and potential applications in drug development. For precise details, consulting specialized databases or scientific literature is recommended.

<p>NCG21, a GPR120 agonist, boosts ERK, Ca²⁺ responses, and GLP-1 in GPR120-expressing cells; raises GLP-1 in mice.</p>

CAS 1079821-35-4

NCG-21

NCG21

Ref: TM-T28140