CAS 108-79-2

2-Hydroxy-4,6-dimethylpyrimidine

Description:

2-Hydroxy-4,6-dimethylpyrimidine, with the CAS number 108-79-2, is an organic compound belonging to the pyrimidine family, characterized by a six-membered aromatic ring containing two nitrogen atoms at positions 1 and 3. This compound features a hydroxyl group (-OH) at the 2-position and two methyl groups (-CH3) at the 4 and 6 positions, contributing to its unique chemical properties. It is typically a white to light yellow crystalline solid, soluble in polar solvents such as water and alcohols, due to the presence of the hydroxyl group. The compound exhibits moderate stability under standard conditions but may undergo reactions typical of pyrimidines, such as nucleophilic substitutions or electrophilic aromatic substitutions. Its hydroxyl group can participate in hydrogen bonding, influencing its reactivity and interactions with other molecules. 2-Hydroxy-4,6-dimethylpyrimidine is of interest in various fields, including pharmaceuticals and agrochemicals, due to its potential biological activities and applications in synthesis.

Formula: C₆H₈N₂O

InChI: InChI=1S/C6H8N2O/c1-4-3-5(2)8-6(9)7-4/h3H,1-2H3,(H,7,8,9)

InChI key: InChIKey=WHEQVHAIRSPYDK-UHFFFAOYSA-N

SMILES: CC1=CC(C)=NC(=O)N1

Synonyms:

• 2(1H)-Pyrimidinone, 4,6-dimethyl-
• 2(1H)-Pyrimidone, 4,6-dimethyl-
• 2-Hydroxy-4,6-dimethylpyrimidine
• 2-Pyrimidinol, 4,6-dimethyl-
• 4,6-Dimethyl-1,2-dihydro-2-pyrimidone
• 4,6-Dimethyl-1,2-dihydropyrimidin-2-one
• 4,6-Dimethyl-2(1H)-Pyrimidinon
• 4,6-Dimethyl-2(1H)-pyrimidinone
• 4,6-Dimethyl-2(1H)-pyrimidone
• 4,6-Dimethyl-2(3H)-pyrimidinone
• 4,6-Dimethyl-2-pyrimidone
• 4,6-dimethyl-2-PYRIMIDINOL
• 4,6-dimethylpyrimidin-2(1H)-one

Ambrisentan Related Compound E (4,6-Dimethylpyrimidin-2-ol)

CAS: 108-79-2

Compounds containing a pyrimidine ring, whether or not hydrogenated, or piperazine ring in the structure, nesoi

Formula: C₆H₈N₂O

Color and Shape: White Off-White Pale Yellow Crystalline Powder

Molecular weight: 124.06366

Ref: 45-1019166

4,6-Dimethylpyrimidin-2(1H)-one

CAS: 108-79-2

Formula: C₆H₈N₂O

Purity: 97%

Color and Shape: Solid

Molecular weight: 124.1405

Ref: IN-DA003HED

4,6-Dimethyl-2-hydroxypyrimidine

CAS: 108-79-2

4,6-Dimethyl-2-hydroxypyrimidine

Formula: C₆H₈N₂O

Purity: 97+%

Color and Shape: faint yellow crystalline solid

Molecular weight: 124.14g/mol

Ref: 54-OR322007

4,6-Dimethyl-2-hydroxypyrimidine

CAS: 108-79-2

Formula: C₆H₈N₂O

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 124.14

Ref: 3B-D2427

Ambrisentan Impurity 2

CAS: 108-79-2

Formula: C₆H₈N₂O

Molecular weight: 124.14

Ref: 4Z-A-3115

Ambrisentan Impurity 2

CAS: 108-79-2

Formula: C₆H₈N₂O

Molecular weight: 124.14

Ref: ST-EA-CP-A15003

4,6-Dimethyl-2-hydroxypyrimidine

Controlled Product

CAS: 108-79-2

Applications 4,6-Dimethyl-2-hydroxypyrimidine is a component of Nicarbazine (N394530), a coccidiostat, which is an antiprotozoal agent that acts upon Coccidia parasites.
References Ksenija Sinigoj, G., et al.: Slovenski Kemijski Dnevi, (2012); Kyung-Woo, L., et al.: Han'guk Kagum Hakhoechi, 39, 17 (2012);

Formula: C₆H₈N₂O

Color and Shape: Neat

Molecular weight: 124.14

Ref: TR-D476275

2-Hydroxy-4,6-dimethylpyrimidine

CAS: 108-79-2

Formula: C₆H₈N₂O

Purity: 98%

Color and Shape: Solid

Molecular weight: 124.143

Ref: 10-F077206

4,6-Dimethyl-2-hydroxypyrimidine

CAS: 108-79-2

4,6-Dimethyl-2-hydroxypyrimidine (DMHP) is an antibiotic drug that inhibits the activity of lipoprotein lipase. DMHP is a broad-spectrum antibiotic that has been shown to have inhibitory effects on bacterial growth in vitro assays. The chemical ionization method was used to measure the amount of DMHP in plasma samples. Results showed that DMHP levels were below the limit of detection in all samples. This suggests that DMHP does not accumulate in the body and may be metabolized quickly. Liquid chromatography with ultra violet light detection was used to analyze the chemical structure of DMHP and found it to be a mixture of two compounds: 4,6-dimethylpyrimidin-2(1H)-one and 2,4,6-trimethoxypyrimidine. The surface methodology was used to identify target tissues for toxicity studies, showing that this compound preferentially binds to liver tissue.

Formula: C₆H₈N₂O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 124.14 g/mol

Ref: 3D-FD12054