CAS: 1080028-80-3 - 1-[(3R)-6,8-Difluoro-3,4-dihydro-2H-1-benzopyran-3-yl]-1,3-dihydro-5-[2-[(phenylmethyl)amino]ethyl]-2H-imidazole-2-thione

Formula: C₂₁H₂₁F₂N₃OS

InChI: InChI=1S/C21H21F2N3OS/c22-16-8-15-9-18(13-27-20(15)19(23)10-16)26-17(12-25-21(26)28)6-7-24-11-14-4-2-1-3-5-14/h1-5,8,10,12,18,24H,6-7,9,11,13H2,(H,25,28)/t18-/m1/s1

InChI key: InChIKey=ZSSLCFLHEFXANG-GOSISDBHSA-N

SMILES: FC=1C=C(F)C=2OCC(N3C(=S)NC=C3CCNCC=4C=CC=CC4)CC2C1

Synonyms:

• 1-[(3R)-6,8-Difluoro-3,4-dihydro-2H-1-benzopyran-3-yl]-1,3-dihydro-5-[2-[(phenylmethyl)amino]ethyl]-2H-imidazole-2-thione
• 2H-Imidazole-2-thione, 1-[(3R)-6,8-difluoro-3,4-dihydro-2H-1-benzopyran-3-yl]-1,3-dihydro-5-[2-[(phenylmethyl)amino]ethyl]-
• Zamicastat
• (R)-5-(2-(Benzylamino)ethyl)-1-(6,8-difluorochroman-3-yl)-1H-imidazole-2(3H)-thione

Zamicastat

CAS: 1080028-80-3

Zamicastat (BIA 5-1058) inhibits DBH, P-gp (IC50=73.8μM), and BCRP (IC50=17.0μM).

• Formula: C₂₁H₂₁F₂N₃OS
• Purity: 99.58%
• Color and Shape: Solid
• Molecular weight: 401.47

Zamicastat

CAS: 1080028-80-3

Zamicastat is a drug that is used in the treatment of vascular dementia, including multi-infarct …

• Formula: C₂₁H₂₁F₂N₃OS
• Purity: Min. 95%
• Molecular weight: 401.5 g/mol