CAS 108026-94-4

(3α,15α,24E)-3-(Acetyloxy)-15-hydroxylanosta-7,9(11),24-trien-26-oic acid

Description:

The chemical substance known as (3α,15α,24E)-3-(Acetyloxy)-15-hydroxylanosta-7,9(11),24-trien-26-oic acid, with the CAS number 108026-94-4, is a triterpenoid compound derived from lanosterol. It features a complex steroidal structure characterized by multiple rings and functional groups, including an acetoxy group and a hydroxyl group, which contribute to its reactivity and biological activity. This compound is notable for its potential pharmacological properties, including anti-inflammatory and anticancer activities, making it of interest in medicinal chemistry and natural product research. Its structural configuration, particularly the E configuration of the double bond at the 24 position, plays a crucial role in its biological interactions. The presence of hydroxyl and acetoxy groups enhances its solubility and reactivity, influencing its behavior in biological systems. Overall, this compound exemplifies the diverse chemistry of triterpenoids and their potential applications in therapeutic contexts.

Formula: C₃₂H₄₈O₅

InChI: InChI=1S/C32H48O5/c1-19(10-9-11-20(2)28(35)36)24-18-26(34)32(8)23-12-13-25-29(4,5)27(37-21(3)33)15-16-30(25,6)22(23)14-17-31(24,32)7/h11-12,14,19,24-27,34H,9-10,13,15-18H2,1-8H3,(H,35,36)/b20-11+/t19-,24-,25+,26+,27-,30-,31-,32-/m1/s1

InChI key: InChIKey=NXZJPJLQVAKBTH-KGEHITQBSA-N

SMILES: C[C@]12C=3C([C@]4(C)[C@@](CC3)(C(C)(C)[C@H](OC(C)=O)CC4)[H])=CC[C@]1(C)[C@@]([C@@H](CC/C=C(/C(O)=O)\C)C)(C[C@@H]2O)[H]

Synonyms:

• Lanosta-7,9(11),24-trien-26-oic acid, 3-(acetyloxy)-15-hydroxy-, (3α,15α,24E)-
• (+)-Ganoderic acid Mf
• (3α,15α,24E)-3-(Acetyloxy)-15-hydroxylanosta-7,9(11),24-trien-26-oic acid
• Ganoderic acid Mf

Ganoderic acid Mf

CAS: 108026-94-4

Ganoderic acid Mf: antitumor triterpenoid, arrests G1 cell cycle, selective for cancer cells, triggers apoptosis via mitochondria.

Formula: C₃₂H₄₈O₅

Color and Shape: Solid

Molecular weight: 512.72

Ref: TM-T75630