CAS 108050-82-4

3-[4-(4-phenyl-3,6-dihydropyridin-1(2H)-yl)butyl]-1H-indol-5-ol hydrochloride

Description:

3-[4-(4-phenyl-3,6-dihydropyridin-1(2H)-yl)butyl]-1H-indol-5-ol hydrochloride, with CAS number 108050-82-4, is a chemical compound that exhibits properties typical of both indole and pyridine derivatives. This substance is characterized by its complex molecular structure, which includes an indole moiety and a dihydropyridine ring, contributing to its potential biological activity. The presence of a hydroxyl group (–OH) on the indole enhances its solubility in polar solvents and may influence its interaction with biological targets. As a hydrochloride salt, it is typically more stable and soluble in aqueous solutions, making it suitable for pharmaceutical applications. The compound may exhibit various pharmacological effects, potentially acting as a modulator of neurotransmitter systems, although specific biological activities would require further investigation. Its synthesis and characterization involve standard organic chemistry techniques, and it is important to handle it with care, adhering to safety protocols due to its potential biological activity.

Formula: C₂₃H₂₇ClN₂O

InChI: InChI=1/C23H26N2O.ClH/c26-21-9-10-23-22(16-21)20(17-24-23)8-4-5-13-25-14-11-19(12-15-25)18-6-2-1-3-7-18;/h1-3,6-7,9-11,16-17,24,26H,4-5,8,12-15H2;1H

SMILES: c1ccc(cc1)C1=CCN(CCCCc2c[nH]c3ccc(cc23)O)CC1.Cl

Synonyms:

• 108050-82-4
• 3-[4-(3,6-Dihydro-4-phenyl-1(2H)-pyridinyl)butyl]-1H-indol-5-ol Monohydrochloride
• 3-[4-(4-Phenyl-3,6-dihydropyridin-1(2H)-yl)butyl]-1H-indol-5-ol hydrochloride (1:1)
• Roxindole hydrochloride

Roxindole Hydrochloride

Controlled Product

CAS: 108050-82-4

Applications Roxindole Hydrochloride is a selective and potent presynaptic D-2 dopamine autoreceptor agonist.
References Lange, J., et al.: Bioorg. Med. Chem. Lett., 9, 1055 (1999); Heinrich, T., et al.: J. Med. Chem., 47, 4677 (2004);

Formula: C₂₃H₂₆N₂O·(HCl)

Color and Shape: Beige

Molecular weight: 346.47 + (36.46)

Ref: TR-R700858

Roxindole hydrochloride

CAS: 108050-82-4

Roxindole hydrochloride is a synthetic compound that is used to treat bowel disease. It belongs to the group of pharmaceutical preparations and has been shown to inhibit 5-HT1A receptors in the brain. Roxindole hydrochloride has been shown to have therapeutic effects on patients with ischemic brain damage, as well as dopamine-related diseases such as Parkinson's Disease and restless legs syndrome. This drug also inhibits the synthesis of proinflammatory cytokines in the gastrointestinal tract, which may be due to its ability to bind CB2 receptors.

Formula: C₂₃H₂₇ClN₂O

Purity: Min. 95%

Molecular weight: 382.9 g/mol

Ref: 3D-IEA05082

Roxindole hydrochloride

CAS: 108050-82-4

Dopamine D2 autoreceptor agonist

Formula: C₂₃H₂₇ClN₂O

Purity: 98%

Color and Shape: Solid

Molecular weight: 382.93

Ref: TM-T23250