CAS 1080632-96-7

4-Aminobenzoic-2,3,5,6-d4 Acid Methyl Ester

Description:

4-Aminobenzoic-2,3,5,6-d4 Acid Methyl Ester, with the CAS number 1080632-96-7, is a deuterated derivative of para-aminobenzoic acid (PABA). This compound features a methyl ester functional group, which enhances its solubility and reactivity in various chemical processes. The presence of deuterium isotopes at the 2, 3, 5, and 6 positions of the aromatic ring provides unique properties for applications in NMR spectroscopy and other analytical techniques, allowing for the study of reaction mechanisms and molecular interactions. As an amino acid derivative, it exhibits characteristics typical of both amines and carboxylic acids, including potential hydrogen bonding and reactivity towards electrophiles. This compound is often utilized in research settings, particularly in studies involving isotopic labeling, drug development, and biochemical assays. Its stability and reactivity make it a valuable tool in organic synthesis and analytical chemistry.

Formula: C₈H₉NO₂

Synonyms:

• 4-Aminobenzoic-2,3,5,6-d4 Acid Methyl Ester
• 4-(Carbomethoxy)aniline-d4

4-Aminobenzoic-​2,​3,​5,​6-​d4 Acid Methyl Ester

Controlled Product

CAS: 1080632-96-7

Applications 4-Aminobenzoic-​2,​3,​5,​6-​d4 Acid Methyl Ester is an intermediate in the synthesis of DMABA-d4 NHS Ester (D678402), which is a labelled DMABA NHS ester (D678400). DMABA NHS ester is a reagent that reacts with the primary amine group of PE lipids. DMABA NHS ester has been used in combination with DMABA NHS ester-d4, -d6, and -d10 to study relative changes in PE lipid abundance before and after radical oxidation.
References Wester, H., et al.: Nucl. Med. Bio., 23, 365 (1996), Frees, D., et al.: Mol. Microbiol., 48, 1565 (2003), Michel, A., et al.: J. Bacteriol., 188, 5783 (2006), Voelker, T., et al.: Bioorg. Med. Chem., 17, 2047 (2009),

Formula: C₈H₅D₄NO₂

Color and Shape: Neat

Molecular weight: 155.19

Ref: TR-A591506