CAS 108081-77-2

N¹-Glutathionyl-spermidine disulfide

CAS: 108081-77-2

The enzyme trypanothione reductase from the insect trypanosomatid Crithidia fasciculata not only uses trypanothione as a substrate, but also this related acyclic disulfide (Km = 149 µM).

Formula: C₃₄H₆₆N₁₂O₁₀S₂

Purity: ≥ 95%

Color and Shape: White Powder

Molecular weight: 867.1

Ref: 01-4015761

N1-Glutathionyl-spermidine disulfide [

CAS: 108081-77-2

N1-Glutathionyl-spermidine disulfide (N1-GS) is a molecule that has been shown to have clinical use in the treatment of chronic hepatitis C infection. The N1-GS molecule is composed of a glutathione (GSH) scaffold with two sulfhydryl groups and an amino acid side chain. N1-GS has a hydrophobic nature, which allows it to penetrate the cellular membrane and enter cells. It is also able to form hydrogen bonds and act as a catalyst for reactions. Fluorescence analysis revealed that this molecule is selective for disulfides over thiols, amines, or alcohols. Disulfides are very important in biological systems since they can be found in enzymes, proteins, and cellular membranes. The insolubility of the N1-GS molecule makes it difficult to analyze its structure using traditional methods such as gas chromatography or nuclear magnetic resonance spectroscopy. However, fluorescence

Formula: C₃₄H₆₆N₁₂O₁₀S₂

Purity: Min. 95%

Molecular weight: 867.09 g/mol

Ref: 3D-FG108363