CAS 108093-90-9

probimane

Description:

Probimane, with the CAS number 108093-90-9, is a chemical compound that belongs to the class of organosilicon compounds. It is primarily recognized for its application in the field of medicinal chemistry, particularly as an antioxidant and a potential therapeutic agent. Probimane exhibits properties that allow it to scavenge free radicals, which can contribute to cellular damage and various diseases. The compound is characterized by its unique structure, which includes a silicon atom bonded to organic groups, enhancing its stability and reactivity. Additionally, probimane has been studied for its potential use in protecting cells from oxidative stress, making it of interest in research related to neurodegenerative diseases and other conditions associated with oxidative damage. Its solubility and interaction with biological systems are also key characteristics that influence its efficacy and application in pharmaceutical formulations. Overall, probimane represents a significant area of study within the realm of chemical substances with therapeutic potential.

Formula: C₂₁H₃₄N₆O₆

InChI: InChI=1/C21H34N6O6/c1-17(25-13-20(30)27(21(31)14-25)16-23-4-8-33-9-5-23)10-24-11-18(28)26(19(29)12-24)15-22-2-6-32-7-3-22/h17H,2-16H2,1H3

InChI key: InChIKey=MAUYWACILHVRLR-UHFFFAOYSA-N

SMILES: C(N1C(=O)CN(C(CN2CC(=O)N(CN3CCOCC3)C(=O)C2)C)CC1=O)N4CCOCC4

Synonyms:

• 2,6-Piperazinedione, 4,4'-(1-methyl-1,2-ethanediyl)bis(1-(4-morpholinylmethyl)-
• 4,4'-Propane-1,2-Diylbis[1-(Morpholin-4-Ylmethyl)Piperazine-2,6-Dione]
• 4,4′-(1-Methyl-1,2-ethanediyl)bis[1-(4-morpholinylmethyl)-2,6-piperazinedione]
• At 2153
• Bis(4-morpholinomethyl-3,5-dioxopiperazin-1-yl)propane
• Mst 02
• Probimane
• MM-159
• CS-2456

Probimane

CAS: 108093-90-9

Probimane

Purity: ≥98%

Molecular weight: 466.54g/mol

Ref: 54-BUP02183

Probimane

CAS: 108093-90-9

Probimane (AT-2153) had Anti-proliferative effects, cell cycle G2/M phase arrest and blocking of chromosome segregation in human tumor cell lines with MST-16.

Formula: C₂₁H₃₄N₆O₆

Purity: 99.91%

Color and Shape: Solid

Molecular weight: 466.54

Ref: TM-T3485

Probimane

CAS: 108093-90-9

Probimane is an anticancer drug that belongs to the class of kinase inhibitors. It is a synthetic analog of the Chinese herb, curcumol, and has been shown to inhibit the growth of tumor cells in vitro and in vivo. Probimane targets cyclin-dependent kinases (CDKs) and other protein kinases involved in cell cycle regulation, leading to apoptosis or programmed cell death. This drug has demonstrated potent activity against a range of human cancer cell lines, including breast, lung, and colon cancer. Probimane has also been found to be excreted in urine, making it a potential candidate for non-invasive monitoring of treatment efficacy.

Formula: C₂₁H₃₄N₆O₆

Purity: Min. 95%

Molecular weight: 466.5 g/mol

Ref: 3D-IEA09390