CAS 108138-46-1: Tosufloxacin

Description: Tosufloxacin is a synthetic fluoroquinolone antibiotic primarily used in veterinary medicine, particularly for treating bacterial infections in animals. It exhibits broad-spectrum antibacterial activity, targeting both Gram-positive and Gram-negative bacteria by inhibiting bacterial DNA gyrase and topoisomerase IV, essential enzymes for DNA replication and transcription. The compound is characterized by its chemical structure, which includes a bicyclic core with a fluorine atom, contributing to its potency and efficacy. Tosufloxacin is typically administered orally and is known for its favorable pharmacokinetic properties, including good tissue penetration and a relatively long half-life. Its use is associated with a lower risk of developing resistance compared to older antibiotics, although caution is advised to prevent potential side effects and ensure responsible use. As with other fluoroquinolones, it may have contraindications and should be used under veterinary guidance to mitigate risks of adverse reactions. Overall, Tosufloxacin represents a valuable tool in the management of bacterial infections in veterinary practice.

Formula: C₁₉H₁₅F₃N₄O₃

InChI: InChI=1S/C19H15F3N4O3/c20-9-1-2-15(13(21)5-9)26-8-12(19(28)29)16(27)11-6-14(22)18(24-17(11)26)25-4-3-10(23)7-25/h1-2,5-6,8,10H,3-4,7,23H2,(H,28,29)

InChI key: InChIKey=WUWFMDMBOJLQIV-UHFFFAOYSA-N

SMILES: O=C(O)C1=CN(C2=NC(=C(F)C=C2C1=O)N3CCC(N)C3)C4=CC=C(F)C=C4F

Synonyms:

• Abbott 61827
• Tosufloxacin (unspecified)
• 7-(3-Amino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid
• A 67107
• CCRIS 6304
• 1,8-Naphthyridine-3-carboxylic acid, 1,4-dihydro-7-(3-amino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-
• 1,8-Naphthyridine-3-carboxylic acid, 7-(3-amino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-
• 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
• Tosufloxacin
• A 61827
• BRN 4913117
• 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid 4-methylbenzenesulfonate (1:1)
• A 67107
• A 61827

Tosufloxacin

CAS: 108138-46-1

• Purity: ≥98%
• Molecular weight: 404.34g/mol

Tosufloxacin

CAS: 108138-46-1

Tosufloxacin (Ozex) is a quinolone antimicrobial agent and potent inhibitor of the metabolism of theophylline.

• Formula: C₁₉H₁₅F₃N₄O₃
• Purity: 99.48%
• Color and Shape: Solid
• Molecular weight: 404.34