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CAS 108274-04-0

:

3-ribofuranosyl-4,9-dihydro-4,6,7-trimethyl-9-oxoimidazo(1,2-a)purine

Description:
3-Ribofuranosyl-4,9-dihydro-4,6,7-trimethyl-9-oxoimidazo(1,2-a)purine, with the CAS number 108274-04-0, is a purine derivative characterized by its complex bicyclic structure, which includes an imidazo ring fused to a purine base. This compound features a ribofuranosyl moiety, indicating the presence of a ribose sugar, which is crucial for its biological activity, particularly in nucleic acid metabolism. The presence of multiple methyl groups at positions 4, 6, and 7 contributes to its lipophilicity and may influence its interaction with biological targets. The keto group at position 9 plays a significant role in its reactivity and stability. This compound is of interest in biochemical research, particularly in the study of nucleoside analogs and their potential therapeutic applications, including antiviral and anticancer properties. Its unique structural features may also affect its solubility and bioavailability, making it a subject of interest in medicinal chemistry.
Formula:C15H19N5O5
InChI:InChI=1/C15H19N5O5/c1-6-7(2)20-13(24)9-12(18(3)15(20)17-6)19(5-16-9)14-11(23)10(22)8(4-21)25-14/h5,8,10-11,14,21-23H,4H2,1-3H3/t8-,10-,11-,14?/m1/s1
SMILES:Cc1c(C)n2c(=O)c3c(n(C)c2n1)n(cn3)C1[C@@H]([C@@H]([C@@H](CO)O1)O)O
Synonyms:
  • 7-Methyl Y nucleoside
  • 9H-Imidazo(1,2-a)purin-9-one, 3,4-dihydro-4,6,7-trimethyl-3-beta-D-ribofuranosyl-
  • 4,6,7-trimethyl-3-(D-ribofuranosyl)-3,4-dihydro-9H-imidazo[1,2-a]purin-9-one
  • 3-Ribofuranosyl-4,9-dihydro-4,6,7-trimethyl-9-oxoimidazo(1,2-a)purine
  • methylwyosine
  • 9H-Imidazo[1,2-a]purin-9-one, 3,4-dihydro-4,6,7-trimethyl-3-β-D-ribofuranosyl-
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  • 3-Ribofuranosyl-4,9-dihydro-4,6,7-trimethyl-9-oxoimidazo(1,2-a)purine
    Biosynth
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    3-Ribofuranosyl-4,9-dihydro-4,6,7-trimethyl-9-oxoimidazo(1,2-a)purine

    CAS:
    <p>3-Ribofuranosyl-4,9-dihydro-4,6,7-trimethyl-9-oxoimidazo(1,2-a)purine is a nucleoside with the chemical formula C8H8N5O5. It is used in research as a phylogenetic marker and index fossil. 3RFP is found as a natural product in some plants and animals, but it can also be synthesized chemically. 3RFP has been shown to posttranscriptionally inhibit rRNA synthesis by binding to the ribonucleotide reductase enzyme. This inhibits the production of RNA needed for protein synthesis and cell division. 3RFP has been shown to have structural diversity that has yet to be fully explored due to its rarity.</p>
    Purity:Min. 95%

    Ref: 3D-NR170482

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