CAS 108294-53-7
:P-IODOCLONIDINE HYDROCHLORIDE
Description:
P-Iodoclonidine hydrochloride is a chemical compound primarily recognized for its role in pharmacology, particularly as an alpha-2 adrenergic agonist. It is a derivative of clonidine, featuring an iodine atom at the para position of the phenyl ring. This modification enhances its pharmacological properties, making it useful in various therapeutic applications, including the management of hypertension and certain psychiatric conditions. The hydrochloride salt form improves its solubility and stability, facilitating its use in formulations. P-Iodoclonidine hydrochloride exhibits a mechanism of action that involves the stimulation of alpha-2 adrenergic receptors in the central nervous system, leading to decreased sympathetic outflow and reduced blood pressure. Its chemical structure includes a piperidine ring, contributing to its lipophilicity and ability to cross the blood-brain barrier. As with many pharmacologically active compounds, safety and efficacy profiles are critical, and ongoing research continues to explore its potential applications and effects in clinical settings.
Formula:C9H8Cl2IN3
InChI:InChI=1/C9H8Cl2IN3/c10-6-3-5(12)4-7(11)8(6)15-9-13-1-2-14-9/h3-4H,1-2H2,(H2,13,14,15)
SMILES:C1CNC(=N1)Nc1c(cc(cc1Cl)I)Cl
Synonyms:- 2-[(2,6-Dichloro-4-Iodophenyl)Imino]Imidazoline Hydrochloride
- P-Iodoclonidine Hydrochloride High Affin
- p-iodoclonidineHCl
- 4-Iodoclonidine
- N-(2,6-dichloro-4-iodophenyl)-4,5-dihydro-1H-imidazol-2-amine
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