CAS 1083076-69-0: Cariprazine hydrochloride
Description:Cariprazine hydrochloride is an atypical antipsychotic medication primarily used in the treatment of schizophrenia and bipolar disorder. It functions as a partial agonist at dopamine D2 and D3 receptors, which contributes to its therapeutic effects while minimizing the risk of extrapyramidal symptoms commonly associated with other antipsychotics. The compound exhibits a unique pharmacological profile, with a higher affinity for the D3 receptor, which is thought to play a role in mood regulation and cognitive function. Cariprazine also has serotonergic activity, impacting serotonin receptors, which may enhance its efficacy in mood stabilization. The substance is typically administered orally and is characterized by its relatively long half-life, allowing for once-daily dosing. In terms of safety, common side effects may include akathisia, insomnia, and gastrointestinal disturbances. As with any medication, careful monitoring for adverse effects and interactions with other drugs is essential during treatment. Overall, Cariprazine hydrochloride represents a significant advancement in the management of certain psychiatric disorders.
Formula:C21H32Cl2N4O·ClH
InChI:InChI=1/C21H32Cl2N4O.ClH/c1-25(2)21(28)24-17-8-6-16(7-9-17)10-11-26-12-14-27(15-13-26)19-5-3-4-18(22)20(19)23;/h3-5,16-17H,6-15H2,1-2H3,(H,24,28);1H/t16-,17-;
InChI key:InChIKey=GPPJWWMREQHLQT-BHQIMSFRNA-N
SMILES:Cl.O=C(NC1CCC(CCN2CCN(C=3C=CC=C(Cl)C3Cl)CC2)CC1)N(C)C
- Synonyms:
- Reagila
- Cariprazine hydrochloride
- RGH 188 hydrochloride
- Urea, N′-[trans-4-[2-[4-(2,3-dichlorophenyl)-1-piperazinyl]ethyl]cyclohexyl]-N,N-dimethyl-, hydrochloride (1:1)

RGH188 hydrochloride
Ref: IN-DA008TEY
1g | 326.00 € | ||
100mg | 213.00 € | ||
250mg | 219.00 € |

Ref: 54-BUP13239
1g | 823.00 € | ||
5g | 1,604.00 € | ||
25mg | 123.00 € | ||
50mg | 187.00 € | ||
100mg | 263.00 € | ||
500mg | 607.00 € |

Cariprazine HCl
Ref: 4Z-C-145001
5mg | To inquire | ||
10mg | To inquire | ||
25mg | To inquire | ||
50mg | To inquire | ||
100mg | To inquire |

Cariprazine hydrochloride
Ref: TM-T8382
5mg | 35.00 € | ||
10mg | 51.00 € | ||
25mg | 84.00 € | ||
50mg | 114.00 € | ||
100mg | 170.00 € | ||
500mg | 406.00 € |

Cariprazine HCl
Ref: 3D-ITB07669
10mg | 220.00 € | ||
25mg | 388.00 € | ||
50mg | 552.00 € | ||
100mg | 837.00 € |