CAS 1083076-69-0

Cariprazine hydrochloride

Description:

Cariprazine hydrochloride is an atypical antipsychotic medication primarily used in the treatment of schizophrenia and bipolar disorder. It functions as a partial agonist at dopamine D2 and D3 receptors, which contributes to its therapeutic effects while minimizing the risk of extrapyramidal symptoms commonly associated with other antipsychotics. The compound exhibits a unique pharmacological profile, with a higher affinity for the D3 receptor, which is thought to play a role in mood regulation and cognitive function. Cariprazine also has serotonergic activity, impacting serotonin receptors, which may enhance its efficacy in mood stabilization. The substance is typically administered orally and is characterized by its relatively long half-life, allowing for once-daily dosing. In terms of safety, common side effects may include akathisia, insomnia, and gastrointestinal disturbances. As with any medication, careful monitoring for adverse effects and interactions with other drugs is essential during treatment. Overall, Cariprazine hydrochloride represents a significant advancement in the management of certain psychiatric disorders.

Formula: C₂₁H₃₃Cl₃N₄O

InChI: InChI=1/C21H32Cl2N4O.ClH/c1-25(2)21(28)24-17-8-6-16(7-9-17)10-11-26-12-14-27(15-13-26)19-5-3-4-18(22)20(19)23;/h3-5,16-17H,6-15H2,1-2H3,(H,24,28);1H/t16-,17-;

InChI key: InChIKey=GPPJWWMREQHLQT-BHQIMSFRNA-N

SMILES: ClC1=C(N2CCN(CC[C@H]3CC[C@H](NC(N(C)C)=O)CC3)CC2)C=CC=C1Cl.Cl

Synonyms:

• Reagila
• Cariprazine hydrochloride
• RGH 188 hydrochloride
• Urea, N′-[trans-4-[2-[4-(2,3-dichlorophenyl)-1-piperazinyl]ethyl]cyclohexyl]-N,N-dimethyl-, hydrochloride (1:1)
• Cariprazine HCl
• RGH188 hydrochloride USP/EP/BP
• Cariprazine(RGH 188)
• Cariprazine HCl(RGH-188 )
• 3-[4-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]cyclohexyl]-1,1-dimethylurea,hydrochloride
• RGH188 hydrochloride
• 3-((1r,4r)-4-(2-(4-(2,3-Dichlorophenyl)piperazin-1-yl)ethyl)cyclohexyl)-1,1-dimethylureahydrochloride

Cariprazine (hydrochloride)

CAS: 1083076-69-0

Formula: C₂₁H₃₃Cl₃N₄O

Purity: 97%

Color and Shape: Solid

Molecular weight: 463.8719

Ref: IN-DA008TEY

Cariprazine hydrochloride

CAS: 1083076-69-0

Cariprazine hydrochloride

Purity: ≥98%

Molecular weight: 463.87g/mol

Ref: 54-BUP13239

Cariprazine HCl

CAS: 1083076-69-0

Formula: C₂₁H₃₂Cl₂N₄O·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 427.41 36.46

Ref: 4Z-C-145001

Cariprazine hydrochloride

CAS: 1083076-69-0

Cariprazine hydrochloride (RGH188 hydrochloride) is an antipsychotic drug, is a D3 and D2 receptor partial agonist((Ki of 0.085 nM and 0.49 nM, respectively)

Formula: C₂₁H₃₃Cl₃N₄O

Purity: 99.78% - >99.99%

Color and Shape: Solid

Molecular weight: 463.87

Ref: TM-T8382

Cariprazine hydrochloride

CAS: 1083076-69-0

Formula: C₂₁H₃₂Cl₂N₄OHCl

Molecular weight: 427.4 : 36.46

Ref: ST-EA-CP-C57006

Cariprazine HCl

CAS: 1083076-69-0

Cariprazine hydrochloride is an antipsychotic drug that belongs to the class of drugs called dopamine receptor antagonists. Cariprazine binds to dopamine receptors in the brain, blocking the effects of dopamine and thereby reducing psychotic symptoms. Cariprazine has been shown to be effective for the treatment of schizophrenia and bipolar disorder in clinical trials. In addition, it has a matrix effect on symptoms that are resistant to other antipsychotic medications. Cariprazine also has pharmacological properties that make it a suitable candidate for drug interactions with other psychotropic medications such as benzodiazepines, antidepressants, opioids, or anticonvulsants.

Formula: C₂₁H₃₃Cl₃N₄O

Purity: Min. 95%

Molecular weight: 463.87 g/mol

Ref: 3D-ITB07669