CAS 108319-06-8

Temafloxacin

Description:

Temafloxacin is a synthetic antibiotic belonging to the fluoroquinolone class, primarily developed for the treatment of bacterial infections. Its chemical structure features a bicyclic core that includes a quinolone moiety, which is essential for its antibacterial activity. Temafloxacin exhibits broad-spectrum efficacy against both Gram-positive and Gram-negative bacteria by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes critical for DNA replication and transcription. This mechanism of action makes it effective against a variety of pathogens, including those responsible for respiratory and urinary tract infections. The compound is characterized by its relatively high bioavailability and the ability to penetrate tissues effectively. However, like other fluoroquinolones, it may be associated with side effects, including gastrointestinal disturbances and potential effects on tendons. Temafloxacin's development was part of a broader effort to enhance the therapeutic options available for treating infections, although its clinical use has been limited compared to other antibiotics in its class.

Formula: C₂₁H₁₈F₃N₃O₃

InChI: InChI=1/C21H18F3N3O3/c1-11-9-26(5-4-25-11)19-8-18-13(7-16(19)24)20(28)14(21(29)30)10-27(18)17-3-2-12(22)6-15(17)23/h2-3,6-8,10-11,25H,4-5,9H2,1H3,(H,29,30)

InChI key: InChIKey=QKDHBVNJCZBTMR-UHFFFAOYSA-N

SMILES: O=C1C=2C(N(C=C1C(O)=O)C3=C(F)C=C(F)C=C3)=CC(=C(F)C2)N4CC(C)NCC4

Synonyms:

• 1-(2,4-Difluorophenyl)-6-Fluoro-7-(3-Methylpiperazin-1-Yl)-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid
• 1-(2,4-Difluorophenyl)-6-fluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid
• 3-Quinolinecarboxylic acid, 1,4-dihydro-1-(2,4-difluorophenyl)-6-fluoro-7- (3-methyl-1-piperazinyl)-4-oxo-
• 3-Quinolinecarboxylic acid, 1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-
• A 62254
• A 63004
• Brn 4301726
• Ccris 6303
• T 1258
• Teflox
• Temac
• Temafloxacin [INN:BAN]
• Temafloxacina
• Temafloxacina [Spanish]
• Temafloxacine
• Temafloxacine [French]
• Temafloxacinum
• Temafloxacinum [Latin]
• Unii-1Wz12Gtt67
• Temafloxacin
• Temafloxacin (Omniflox)
• TEMAFLOXACIN USP/EP/BP
• 6-Fluoro-1-(2,4-difluorophenyl)-7-(3-methylpiperazin-1-yl)-1,4-dihydro-4-oxoquinoline-3-carboxylic acid
• 1-(2,4-Difluorophenyl)-6-fluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl) -4-oxo-3-quinoline-carboxylic acid
• TeMafloxacin HCl
• 1-(2,4-difluorophenyl)-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxo-quino line-3-carboxylic acid hydrochloride
• 3-Quinolinecarboxylicacid,1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-
• Omniflox
• AKOS 92085

1-(2,4-Difluorophenyl)-6-fluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid

CAS: 108319-06-8

Formula: C₂₁H₁₈F₃N₃O₃

Purity: %

Color and Shape: Solid

Molecular weight: 417.3811

Ref: IN-DA008UY9

Temafloxacin

CAS: 108319-06-8

Temafloxacin

Purity: ≥98%

Molecular weight: 417.38g/mol

Ref: 54-BUP00227

Temafloxacin

CAS: 108319-06-8

Formula: C₂₁H₁₈F₃N₃O₃

Molecular weight: 417.38

Ref: 7W-GA1115

Temafloxacin

CAS: 108319-06-8

Temafloxacin (Omniflox) is an antibiotic for respiratory, genital, urinary, and skin infections.

Formula: C₂₁H₁₈F₃N₃O₃

Purity: 99.24%

Color and Shape: Solid

Molecular weight: 417.38

Ref: TM-T19794

Temafloxacin

Controlled Product

CAS: 108319-06-8

Applications Temafloxacin is an antimicrobial quinolone drug.
References Goel, H., et. al.: Int. J. Pharmaceut., 415, 158 (2011)

Formula: C₂₁H₁₈F₃N₃O₃

Color and Shape: Neat

Molecular weight: 417.38

Ref: TR-T017185

Temafloxacin

CAS: 108319-06-8

Purity: 98+%

Molecular weight: 417.388

Ref: 10-F979515

Temafloxacin-d7

Controlled Product

CAS: 108319-06-8

Formula: C₂₁H₁₁D₇F₃N₃O₃

Color and Shape: Neat

Molecular weight: 424.42

Ref: TR-T017187