CAS 108319-06-8: Temafloxacin

Description: Temafloxacin is a synthetic antibiotic belonging to the fluoroquinolone class, primarily developed for the treatment of bacterial infections. Its chemical structure features a bicyclic core that includes a quinolone moiety, which is essential for its antibacterial activity. Temafloxacin exhibits broad-spectrum efficacy against both Gram-positive and Gram-negative bacteria by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes critical for DNA replication and transcription. This mechanism of action makes it effective against a variety of pathogens, including those responsible for respiratory and urinary tract infections. The compound is characterized by its relatively high bioavailability and the ability to penetrate tissues effectively. However, like other fluoroquinolones, it may be associated with side effects, including gastrointestinal disturbances and potential effects on tendons. Temafloxacin's development was part of a broader effort to enhance the therapeutic options available for treating infections, although its clinical use has been limited compared to other antibiotics in its class.

Formula: C₂₁H₁₈F₃N₃O₃

InChI: InChI=1S/C21H18F3N3O3/c1-11-9-26(5-4-25-11)19-8-18-13(7-16(19)24)20(28)14(21(29)30)10-27(18)17-3-2-12(22)6-15(17)23/h2-3,6-8,10-11,25H,4-5,9H2,1H3,(H,29,30)

InChI key: InChIKey=QKDHBVNJCZBTMR-UHFFFAOYSA-N

SMILES: O=C(O)C1=CN(C2=CC=C(F)C=C2F)C3=CC(=C(F)C=C3C1=O)N4CCNC(C)C4

Synonyms:

• 1-(2,4-Difluorophenyl)-6-Fluoro-7-(3-Methylpiperazin-1-Yl)-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid
• 1-(2,4-Difluorophenyl)-6-fluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid
• 3-Quinolinecarboxylic acid, 1,4-dihydro-1-(2,4-difluorophenyl)-6-fluoro-7- (3-methyl-1-piperazinyl)-4-oxo-
• 3-Quinolinecarboxylic acid, 1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-
• A 62254
• A 63004
• Brn 4301726
• Ccris 6303
• T 1258
• Teflox
• Temac
• Temafloxacin [INN:BAN]
• Temafloxacina
• Temafloxacina [Spanish]
• Temafloxacine
• Temafloxacine [French]
• Temafloxacinum
• Temafloxacinum [Latin]
• Unii-1Wz12Gtt67
• Temafloxacin

TEMAFLOXACIN

CAS: 108319-06-8

• Formula: C₂₁H₁₈F₃N₃O₃
• Purity: %
• Color and Shape: Solid
• Molecular weight: 417.3811

Temafloxacin

CAS: 108319-06-8

• Formula: C₂₁H₁₈F₃N₃O₃
• Molecular weight: 417.38

Temafloxacin

CAS: 108319-06-8

Temafloxacin (Omniflox) is an antibiotic for respiratory, genital, urinary, and skin infections.

• Formula: C₂₁H₁₈F₃N₃O₃
• Purity: 98.40%
• Color and Shape: Solid
• Molecular weight: 417.38

Temafloxacin-d7

CAS: 108319-06-8

• Formula: C₂₁H₁₁D₇F₃N₃O₃
• Color and Shape: Neat
• Molecular weight: 424.42

Temafloxacin

CAS: 108319-06-8

Applications Temafloxacin is an antimicrobial quinolone drug. References Goel, H., et. al.: Int. J. Pharmaceut., …

• Formula: C₂₁H₁₈F₃N₃O₃
• Color and Shape: Neat
• Molecular weight: 417.38

Temafloxacin

CAS: 108319-06-8

Temafloxacin is a broad-spectrum fluoroquinolone antibacterial agent that is used in the treatment of pulmonary, …

• Formula: C₂₁H₁₈F₃N₃O₃
• Purity: Min. 95%
• Molecular weight: 417.38 g/mol