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CAS 108321-39-7

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Fmoc-D-Asn-OH

Description:
Fmoc-D-Asn-OH, or 9-fluorenylmethoxycarbonyl-D-asparagine, is a protected amino acid commonly used in peptide synthesis. It features a fluorenylmethoxycarbonyl (Fmoc) group, which serves as a protective group for the amino functionality, allowing for selective reactions during peptide assembly. The D-asparagine component indicates that it is the D-enantiomer of asparagine, an amino acid that plays a crucial role in protein synthesis and metabolism. Fmoc-D-Asn-OH is typically a white to off-white solid and is soluble in organic solvents such as dimethylformamide (DMF) and dimethyl sulfoxide (DMSO), but less soluble in water. The Fmoc group can be removed under basic conditions, facilitating the subsequent coupling of amino acids in solid-phase peptide synthesis. This compound is valuable in the field of biochemistry and pharmaceutical research, particularly for the development of peptides with specific biological activities. Its CAS number, 108321-39-7, uniquely identifies this chemical substance in chemical databases.
Formula:C19H18N2O5
InChI:InChI=1/C19H18N2O5/c20-17(22)9-16(18(23)24)21-19(25)26-10-15-13-7-3-1-5-11(13)12-6-2-4-8-14(12)15/h1-8,15-16H,9-10H2,(H2,20,22)(H,21,25)(H,23,24)/t16-/m1/s1
SMILES:c1ccc2c(c1)c1ccccc1C2COC(=N[C@H](CC(=N)O)C(=O)O)O
Synonyms:
  • NALPHA-9-Fluorenylmethoxycarbonyl-D-asparagine
  • N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-asparagine
  • N-α-Fmoc-D-asparagine
  • Fmoc-D-asparagine
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