CAS 108322-03-8
:N-succinyl-ala-ala-val-ala*P-nitroanilide
Description:
N-succinyl-ala-ala-val-ala*P-nitroanilide, with the CAS number 108322-03-8, is a synthetic peptide substrate commonly used in biochemical research, particularly in studies involving proteolytic enzymes. This compound features a succinyl group that enhances its solubility and stability, making it suitable for enzymatic assays. The peptide sequence consists of alanine and valine residues, which contribute to its specificity for certain proteases. The presence of the p-nitroanilide moiety serves as a chromogenic indicator, allowing for the quantification of enzymatic activity through colorimetric changes upon cleavage by enzymes. This substrate is particularly valuable in the study of serine proteases and can be utilized in various assays to monitor enzyme kinetics and activity. Its characteristics include good solubility in aqueous solutions, stability under physiological conditions, and a clear response to enzymatic cleavage, making it a useful tool in both academic and industrial research settings.
Formula:C24H34N6O9
InChI:InChI=1/C24H34N6O9/c1-12(2)20(24(37)27-14(4)22(35)28-16-6-8-17(9-7-16)30(38)39)29-23(36)15(5)26-21(34)13(3)25-18(31)10-11-19(32)33/h6-9,12-15,20H,10-11H2,1-5H3,(H,25,31)(H,26,34)(H,27,37)(H,28,35)(H,29,36)(H,32,33)
SMILES:CC(C)C(C(=NC(C)C(=O)Nc1ccc(cc1)N(=O)=O)O)N=C(C(C)N=C(C(C)N=C(CCC(=O)O)O)O)O
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Found 3 products.
Suc-Ala-Ala-Val-Ala-pNA
CAS:Suc-AAVA-pNA has been used for assaying hamster chymase 2.Formula:C24H34N6O9Purity:> 99%Color and Shape:Light Beige PowderMolecular weight:550.57N-Succinyl-Ala-Ala-Val-Ala p-nitroanilide
CAS:Formula:C24H34N6O9Purity:≥ 98.0%Color and Shape:White to off-white powderMolecular weight:550.56Suc-Ala-Ala-Val-Ala-pNA
CAS:<p>Suc-Ala-Ala-Val-Ala-pNA is a synthetic peptide that is structurally similar to the natural peptide Vasoactive Intestinal Peptide. The amino acid sequence of this peptide is identical to that of the natural peptide with the exception of two additional amino acids, Ala and Val. Suc-Ala-Ala-Val-Ala-pNA has been shown to have vasoactive properties and it can be used for the treatment of inflammatory diseases such as Crohn's disease. This peptide has also been shown to inhibit protease activity by binding to the reactive site on serine proteases, which are involved in the degradation of extracellular proteins.</p>Formula:C24H34N6O9Purity:Min. 95%Molecular weight:550.56 g/mol


