CAS 108351-52-6

glidobactin C

Description:

Glidobactin C is a natural product classified as a secondary metabolite, specifically belonging to the class of polyketides. It is produced by certain strains of bacteria, notably those in the genus *Streptomyces*. This compound exhibits a complex molecular structure characterized by multiple functional groups, which contribute to its biological activity. Glidobactin C has garnered interest due to its potential antimicrobial properties, making it a subject of research in the field of medicinal chemistry. Its mechanism of action may involve interference with bacterial cell wall synthesis or other vital cellular processes. Additionally, glidobactin C may exhibit cytotoxic effects against various cancer cell lines, highlighting its potential as a lead compound in drug development. The compound's stability, solubility, and reactivity can vary based on environmental conditions, which are important factors to consider in both laboratory and therapeutic applications. Overall, glidobactin C represents a promising area of study for its potential applications in pharmaceuticals and biotechnology.

Formula: C₂₉H₄₈N₄O₆

InChI: InChI=1/C29H48N4O6/c1-4-5-6-7-8-9-10-11-12-13-14-15-26(37)33-27(22(3)34)29(39)32-24-20-23(35)18-19-30-25(36)17-16-21(2)31-28(24)38/h12-17,21-24,27,34-35H,4-11,18-20H2,1-3H3,(H,30,36)(H,31,38)(H,32,39)(H,33,37)/b13-12+,15-14+,17-16-/t21-,22+,23-,24-,27-/m0/s1

Synonyms:

• Antibiotic BU-2867TC
• BU-2867TC
• Antibioti BU-2867TC
• (2E,4E)-N-[(1S,2R)-2-Hydroxy-1-[[[[(3E,5S,8S,10S)-10-hydroxy-5-methyl-2,7-dioxo-1,6-diazacyclododeca-3-en]-8-yl]amino]carbonyl]propyl]-2,4-tetradecadienamide
• glidobactin C
• 2,4-Tetradecadienamide, N-(2-hydroxy-1-(((10-hydroxy-5-methyl-2,7-dioxo-1,6-diazacyclododec-3-en-8-yl)amino)carbonyl)propyl)-, (5S-(3E,5R*,8R*(1R*(2E,4E),2S*),10R*))-
• (2E,4E)-N-[(1S,2R)-2-hydroxy-1-{[(3Z,5S,8S,10S)-10-hydroxy-5-methyl-2,7-dioxo-1,6-diazacyclododec-3-en-8-yl]carbamoyl}propyl]tetradeca-2,4-dienamide

Glidobactin C

CAS: 108351-52-6

Glidobactin C (GlbC) is an antitumor antibiotic with activity against pathogenic fungi and yeasts. It exhibits antifungal properties against Candida albicans and Aspergillus fumigatus, with a minimum inhibitory concentration (MIC) of 0.8 μg/mL. Additionally, Glidobactin C prolongs the survival time of mice inoculated with leukemia P388 cells.

Formula: C₂₉H₄₈N₄O₆

Color and Shape: Solid

Molecular weight: 548.715

Ref: TM-TN10554