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CAS 108437-28-1

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Binfloxacin

Description:
Binfloxacin is a synthetic fluoroquinolone antibiotic characterized by its broad-spectrum antibacterial activity. It is primarily effective against a variety of Gram-positive and Gram-negative bacteria, making it useful in treating various bacterial infections. The compound features a bicyclic core structure typical of fluoroquinolones, which includes a fluorine atom that enhances its potency and spectrum of activity. Binfloxacin operates by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes crucial for DNA replication and transcription, thereby disrupting bacterial cell division. It is generally administered orally and exhibits good bioavailability. The substance is known for its favorable pharmacokinetic properties, including a relatively long half-life, which allows for less frequent dosing. However, like other antibiotics, it may be associated with potential side effects, including gastrointestinal disturbances and, in rare cases, tendon damage. As with all antibiotics, appropriate use is essential to minimize the risk of developing antibiotic resistance.
Formula:C19H22FN3O3
InChI:InChI=1/C19H22FN3O3/c1-2-22-11-14(19(25)26)18(24)13-9-15(20)17(10-16(13)22)23-8-7-21-5-3-12(23)4-6-21/h9-12H,2-8H2,1H3,(H,25,26)
Synonyms:
  • Binfloxacin [USAN:INN]
  • UNII-78VM28ZA2H
  • CP-73,049
  • 7-(1,4-diazabicyclo[3.2.2]non-4-yl)-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
  • CP 73049
  • 7-(1,4-Diazabicyclo(3.2.2)non-4-yl)-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
  • 3-Quinolinecarboxylic acid, 7-(1,4-diazabicyclo(3.2.2)non-4-yl)-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-
  • CP-73
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