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CAS 108437-64-5

:

12-Oxo-5Z,8Z,10E,14Z-eicosatetraenoic acid

Description:
12-Oxo-5Z,8Z,10E,14Z-eicosatetraenoic acid, commonly referred to as 12-oxo-ETE, is a bioactive lipid molecule that belongs to the family of eicosanoids. It is characterized by its long carbon chain, consisting of 20 carbon atoms and four double bonds, which contribute to its unsaturated nature. The presence of a keto group at the 12th carbon position is a distinctive feature that influences its biological activity. This compound is known to play a role in various physiological processes, including inflammation and cell signaling. It is often studied for its potential implications in cardiovascular health and metabolic disorders. The structural configuration, indicated by the Z and E notations, refers to the specific geometric arrangements of the double bonds, which can affect the molecule's reactivity and interaction with biological targets. As a naturally occurring compound, 12-oxo-ETE is typically found in various biological systems and can be synthesized through enzymatic pathways involving arachidonic acid. Its study is significant in understanding lipid metabolism and the development of therapeutic agents.
Formula:C20H30O3
InChI:InChI=1S/C20H30O3/c1-2-3-4-5-10-13-16-19(21)17-14-11-8-6-7-9-12-15-18-20(22)23/h7-11,13-14,17H,2-6,12,15-16,18H2,1H3,(H,22,23)/b9-7-,11-8-,13-10-,17-14+
InChI key:InChIKey=GURBRQGDZZKITB-VXBMJZGYSA-N
SMILES:C(\C(C/C=C\CCCCC)=O)=C/C=C\C/C=C\CCCC(O)=O
Synonyms:
  • (5Z,8Z,10E,14Z)-12-Oxo-5,8,10,14-eicosatetraenoic acid
  • (5Z,8Z,10E,14Z)-12-oxoicosa-5,8,10,14-tetraenoic acid
  • 12-Oxo-5Z,8Z,10E,14Z-Eicosatetraenoic Acid
  • 12-Oxo-ETE
  • 12-Oxoete
  • 5,8,10,14-Eicosatetraenoic acid, 12-oxo-, (5Z,8Z,10E,14Z)-
  • 5,8,10,14-Eicosatetraenoic acid, 12-oxo-, (E,Z,Z,Z)-
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Found 2 products.
  • 12-OxoETE
    Targetmol
    + Info

    12-OxoETE

    CAS:
    12-OxoETE is an endogenous arachidonic acid metabolite. 12-KETE induces transient intracytoplasmic free calcium ion concentration via LTB4 receptor.
    Formula:C20H30O3
    Color and Shape:Solid
    Molecular weight:318.45

    Ref: TM-T37972

    25µg
    489.00€
    50µg
    899.00€
    100µg
    1,647.00€
    250µg
    3,647.00€
  • 12-oxo-5(Z),8(Z),10(E),14(Z)-eicosatetraenoic acid
    Larodan
    + Info

    12-oxo-5(Z),8(Z),10(E),14(Z)-eicosatetraenoic acid

    CAS:
    Formula:C20H30O3
    Purity:>90%
    Color and Shape:In solution, Ethanol
    Molecular weight:318.45

    Ref: 48-13-2041

    50µg
    369.00€
    100µg
    665.00€