CAS 108466-89-3

BocNH-PEG2-CH2COOH

Description:

BocNH-PEG2-CH2COOH, also known as a Boc-protected amino acid derivative linked to polyethylene glycol (PEG), is characterized by its unique structure that combines a Boc (tert-butyloxycarbonyl) protecting group with a PEG moiety and a carboxylic acid functional group. The presence of the Boc group provides stability and protection to the amine during synthesis and subsequent reactions, while the PEG segment enhances solubility in aqueous environments and improves biocompatibility. The carboxylic acid group contributes to the compound's ability to participate in various chemical reactions, including esterification and amidation. This compound is often utilized in bioconjugation, drug delivery systems, and the development of biomaterials due to its favorable properties, such as low toxicity and the ability to form stable conjugates with proteins or other biomolecules. Its versatility makes it a valuable tool in medicinal chemistry and polymer science, particularly in the design of targeted therapies and controlled release systems.

Synonyms:

• 3,8,11-Trioxa-5-azatridecan-13-oic acid
• t-boc-N-amido-PEG2-acetic acid
• 3,8,11-Trioxa-5-azatridecan-13-oic acid, 2,2-diMethyl-4-oxo-
• t-Boc-N-amido-PEG2-CH2CO2H
• Boc-N-amido-PEG2-CH2CO2H
• 2-[2-[2-[(2-Methylpropan-2-yl)oxycarbonylaMino]ethoxy]ethoxy]acetic acid
• 8-tert-butyloxycarbonylaMino-3,6-dioxaoctanoic acid
• Boc-AEEA
• 2,2-DiMethyl-4-oxo-3,8,11-trioxa-5-azatridecan-13-oic acid

Boc-8-amino-3,6-dioxaoctanoic acid

CAS: 108466-89-3

Formula: C₁₁H₂₁NO₆

Purity: 95%

Color and Shape: Liquid

Molecular weight: 263.2875

Ref: IN-DA0039XU

Boc-NH-PEG2-CH2COOH

CAS: 108466-89-3

Boc-NH-PEG2-CH2COOH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.

Formula: C₁₁H₂₁NO₆

Color and Shape: Solid

Molecular weight: 263.29

Ref: TM-T14738

t-Boc-N-amido-PEG2-CH2CO2H

CAS: 108466-89-3

t-Boc-N-amido-PEG2-CH2CO2H

Formula: C₁₁H₂₁NO₆

Purity: 97% (nmr) (Typical Value in Batch COA)

Color and Shape: yellow liquid

Molecular weight: 263.29g/mol

Ref: 54-BIPG1825

2,2-Dimethyl-4-oxo-3,8,11-trioxa-5-azatridecan-13-oic acid

CAS: 108466-89-3

Formula: C₁₁H₂₁NO₆

Purity: 97%

Color and Shape: Liquid

Molecular weight: 263.29

Ref: 10-F364029

8-tert-Butyloxycarbonylamino-3,6-dioxaoctanoic Acid

Controlled Product

CAS: 108466-89-3

Formula: C₁₁H₂₁NO₆

Color and Shape: Neat

Molecular weight: 263.288

Ref: TR-B694050

N-(tert-Butyloxycarbonyl)-8-amino-3,6-dioxaoctanoic acid

CAS: 108466-89-3

N-(tert-Butyloxycarbonyl)-8-amino-3,6-dioxaoctanoic acid is a potential drug for hypercholesterolemia. It has been shown to lower LDL cholesterol and triglycerides levels in monkeys. The compound is orally bioavailable and can be taken orally. This drug also has the potential to be developed as a PCSK9 (proprotein convertase subtilisin/kexin type 9) inhibitor.

Formula: C₁₁H₂₁NO₆

Purity: Min. 95%

Color and Shape: Clear Liquid

Molecular weight: 263.29 g/mol

Ref: 3D-FN161445