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CAS 1084953-47-8

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5-Trifluoromethylpyridine-3-boronic acid pinacol ester

Description:
5-Trifluoromethylpyridine-3-boronic acid pinacol ester is an organoboron compound characterized by the presence of a pyridine ring substituted with a trifluoromethyl group and a boronic acid moiety that is esterified with pinacol. This compound typically exhibits properties associated with both boron and nitrogen functionalities, making it useful in various chemical reactions, particularly in Suzuki coupling reactions, which are pivotal in the synthesis of biaryl compounds. The trifluoromethyl group enhances the compound's lipophilicity and can influence its reactivity and stability. As a boronic ester, it is generally stable under standard conditions but can undergo hydrolysis to release the corresponding boronic acid. The presence of the pinacol group provides steric hindrance, which can affect the reactivity of the boron center. This compound is of interest in medicinal chemistry and materials science due to its potential applications in drug development and organic synthesis. Safety and handling precautions should be observed, as with all organoboron compounds, due to their reactivity and potential toxicity.
Formula:C12H17BF3NO3
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