CAS 108527-83-9

Benzothiazolium, 2-[3-(1,3-dihydro-1,3,3-trimethyl-2H-indol-2-ylidene)-1-propen-1-yl]-3-ethyl-, iodide (1:1)

Description:

Benzothiazolium, 2-[3-(1,3-dihydro-1,3,3-trimethyl-2H-indol-2-ylidene)-1-propen-1-yl]-3-ethyl-, iodide (1:1), with CAS number 108527-83-9, is a complex organic compound characterized by its unique structural features, including a benzothiazolium core and an indole-derived substituent. This compound typically exhibits properties associated with quaternary ammonium salts, such as being a cationic species due to the presence of the iodide ion. It may display notable solubility in polar solvents and can participate in various chemical reactions, including nucleophilic substitutions and electrophilic additions. The presence of the indole moiety suggests potential biological activity, which could be explored in pharmacological contexts. Additionally, the compound's structural configuration may influence its optical properties, making it of interest in materials science and organic electronics. Overall, its diverse characteristics make it a subject of interest in both synthetic chemistry and potential applications in medicinal chemistry.

Formula: C₂₃H₂₅N₂S·I

InChI: InChI=1S/C23H25N2S.HI/c1-5-25-19-13-8-9-14-20(19)26-22(25)16-10-15-21-23(2,3)17-11-6-7-12-18(17)24(21)4;/h6-16H,5H2,1-4H3;1H/q+1;/p-1

InChI key: InChIKey=TWBRXRGFFUATNI-UHFFFAOYSA-M

SMILES: CC1(C)C=2C(N(C)C1=CC=CC3=[N+](CC)C=4C(S3)=CC=CC4)=CC=CC2.[I-]

Synonyms:

• 2-(3-(3-Ethylbenzo[d]thiazol-2(3H)-ylidene)prop-1-en-1-yl)-1,3,3-trimethyl-3H-indol-1-ium iodide
• 2-[3-(1,3-Dihydro-1,3,3-trimethyl-2H-indol-2-ylidene)-1-propenyl]-3-ethyl-benzothiazoium iodide
• Ac 93253
• Benzothiazolium, 2-[3-(1,3-dihydro-1,3,3-trimethyl-2H-indol-2-ylidene)-1-propenyl]-3-ethyl-, iodide
• Benzothiazolium, 2-[3-(1,3-dihydro-1,3,3-trimethyl-2H-indol-2-ylidene)-1-propenyl]-3-ethyl-,iodide (9CI)
• Benzothiazolium, 2-[3-(1,3-dihydro-1,3,3-trimethyl-2H-indol-2-ylidene)-1-propen-1-yl]-3-ethyl-, iodide (1:1)

AC-93253 iodide

CAS: 108527-83-9

Formula: C₂₃H₂₅N₂SI

Molecular weight: 488.43

Ref: 7W-GK4984

AC-93253 Iodide

Controlled Product

CAS: 108527-83-9

Formula: C₂₃H₂₅N₂S•I

Color and Shape: Neat

Molecular weight: 488.44

Ref: TR-A192220

AC-93253 iodide

CAS: 108527-83-9

AC-93253 iodide is a drug that is being developed for the treatment of prostate cancer. The mechanism of action of AC-93253 iodide is still not known, but it has been shown to inhibit epidermal growth factor (EGF) receptor proliferation in prostate cancer cells and suppress the proliferation of other cancerous cells. Clinical studies have demonstrated that this drug has anti-leukemic activity, and it was shown to be effective against a wide variety of cancers in vitro. AC-93253 iodide inhibits transcriptional regulation by binding to the polymerase chain reaction (PCR) transcriptase during DNA replication. This inhibition prevents the extension of DNA chains and halts DNA synthesis.

Formula: C₂₃H₂₅N₂SI

Purity: Min. 95%

Molecular weight: 488.43 g/mol

Ref: 3D-IEA52783

AC-93253 iodide

CAS: 108527-83-9

AC-93253 iodide is a selective inhibitor of SIRT2. It significantly enhances the acetylation of tubulin p53 and histone H4.

Formula: C₂₃H₂₅IN₂S

Purity: 98%

Color and Shape: Solid

Molecular weight: 488.43

Ref: TM-T24998