CAS 108605-62-5: 2-Cyano-3-hydroxy-N-(4-trifluoromethylphenyl)crotonamide

Description: 2-Cyano-3-hydroxy-N-(4-trifluoromethylphenyl)crotonamide, identified by its CAS number 108605-62-5, is an organic compound characterized by its unique functional groups and structural features. It contains a cyano group (-CN), a hydroxyl group (-OH), and an amide linkage, which contribute to its chemical reactivity and potential applications in various fields, including pharmaceuticals and agrochemicals. The presence of the trifluoromethyl group (-CF3) on the phenyl ring enhances its lipophilicity and can influence its biological activity, making it a subject of interest in medicinal chemistry. This compound is typically a solid at room temperature and may exhibit moderate solubility in organic solvents. Its synthesis involves multi-step reactions, often requiring careful control of reaction conditions to achieve the desired purity and yield. The compound's properties, such as melting point, boiling point, and spectral characteristics, are essential for understanding its behavior in different environments and its potential interactions with other substances.

Formula: C₁₂H₉F₃N₂O₂

InChI: InChI=1S/C12H9F3N2O2/c1-7(18)10(6-16)11(19)17-9-4-2-8(3-5-9)12(13,14)15/h2-5,18H,1H3,(H,17,19)

InChI key: InChIKey=UTNUDOFZCWSZMS-UHFFFAOYSA-N

SMILES: N#CC(C(=O)NC1=CC=C(C=C1)C(F)(F)F)=C(O)C

Synonyms:

• (2Z)-2-(hydroxy{[4-(trifluoromethyl)phenyl]amino}methylidene)-3-oxobutanenitrile
• (Z)-2-Cyano-alpha'alpha'alpha-trifluoro-3-hydroxy-p-crotonotoluidide
• 2-Butenamide, 2-cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)-
• 2-Cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)-2-butenamide
• 2-Cyano-3-hydroxy-N-(4-trifluoromethylphenyl)crotonamide
• 2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide
• A 771726
• A771726
• Active metabolite of leflunomide
• Flucyamide
• Hmr 1726
• Malononitrilamide
• N-(4-Trifluoromethylphenyl)-2-cyano-2-hydroxycrotonamide
• Su 20
• Teriflunomide
• Teriflunomide [INN]
• Unii-1C058Ikg3B

A77 1726

CAS: 108605-62-5

• Formula: C₁₂H₉F₃N₂O₂
• Purity: %
• Color and Shape: Solid
• Molecular weight: 270.2073

2-Cyano-3-hydroxy-N-(4-trifluoromethylphenyl)crotonamide

CAS: 108605-62-5

• Purity: 97%
• Molecular weight: 270.21g/mol

(E/Z)-Teriflunomide

CAS: 108605-62-5

• Purity: 98%
• Molecular weight: 270.21g/mol

(E/Z)-Teriflunomide

CAS: 108605-62-5

(E/Z)-Teriflunomide (Aubagio), a orally-available Pyrimidine Synthesis Inhibitor, is used to treat relapsing multiple sclerosis.

• Formula: C₁₂H₉F₃N₂O₂
• Purity: 99.49% - 99.76%
• Color and Shape: White Solid
• Molecular weight: 270.21

A77 1726 (E/Z) Mixture

CAS: 108605-62-5

Impurity Leflunomide USP Related Compound B Applications rac A77 1726 is the active metabolite of …

• Formula: C₁₂H₉F₃N₂O₂
• Color and Shape: Neat
• Molecular weight: 270.21

2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide

CAS: 108605-62-5

Please enquire for more information about 2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide including the price, delivery time and more detailed …

• Formula: C₁₂H₉F₃N₂O₂
• Purity: Min. 95%
• Molecular weight: 270.21 g/mol