CAS 108605-62-5: 2-Cyano-3-hydroxy-N-(4-trifluoromethylphenyl)crotonamide
Description:2-Cyano-3-hydroxy-N-(4-trifluoromethylphenyl)crotonamide, identified by its CAS number 108605-62-5, is an organic compound characterized by its unique functional groups and structural features. It contains a cyano group (-CN), a hydroxyl group (-OH), and an amide linkage, which contribute to its chemical reactivity and potential applications in various fields, including pharmaceuticals and agrochemicals. The presence of the trifluoromethyl group (-CF3) on the phenyl ring enhances its lipophilicity and can influence its biological activity, making it a subject of interest in medicinal chemistry. This compound is typically a solid at room temperature and may exhibit moderate solubility in organic solvents. Its synthesis involves multi-step reactions, often requiring careful control of reaction conditions to achieve the desired purity and yield. The compound's properties, such as melting point, boiling point, and spectral characteristics, are essential for understanding its behavior in different environments and its potential interactions with other substances.
Formula:C12H9F3N2O2
InChI:InChI=1S/C12H9F3N2O2/c1-7(18)10(6-16)11(19)17-9-4-2-8(3-5-9)12(13,14)15/h2-5,18H,1H3,(H,17,19)
InChI key:InChIKey=UTNUDOFZCWSZMS-UHFFFAOYSA-N
SMILES:N#CC(C(=O)NC1=CC=C(C=C1)C(F)(F)F)=C(O)C
- Synonyms:
- (2Z)-2-(hydroxy{[4-(trifluoromethyl)phenyl]amino}methylidene)-3-oxobutanenitrile
- (Z)-2-Cyano-alpha'alpha'alpha-trifluoro-3-hydroxy-p-crotonotoluidide
- 2-Butenamide, 2-cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)-
- 2-Cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)-2-butenamide
- 2-Cyano-3-hydroxy-N-(4-trifluoromethylphenyl)crotonamide
- 2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide
- A 771726
- A771726
- Active metabolite of leflunomide
- Flucyamide
- See more synonyms
- Hmr 1726
- Malononitrilamide
- N-(4-Trifluoromethylphenyl)-2-cyano-2-hydroxycrotonamide
- Su 20
- Teriflunomide
- Teriflunomide [INN]
- Unii-1C058Ikg3B
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Ref: IN-DA008R9F
1g | 170.00 € | ||
5g | 636.00 € | ||
25mg | 53.00 € | ||
100mg | 56.00 € | ||
250mg | 75.00 € |
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2-Cyano-3-hydroxy-N-(4-trifluoromethylphenyl)crotonamide
Ref: 54-PC105175
1g | 133.00 € | ||
5g | 497.00 € | ||
25g | 2,125.00 € | ||
100mg | 43.00 € | ||
250mg | 56.00 € |
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(E/Z)-Teriflunomide
Ref: TM-T3044
50mg | 37.00 € | ||
100mg | 52.00 € | ||
1mL*10mM (DMSO) | 34.00 € |
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A77 1726 (E/Z) Mixture
Controlled ProductRef: TR-A771720
1g | 1,521.00 € | ||
50mg | 160.00 € | ||
100mg | 213.00 € |
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2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide
Controlled ProductRef: 3D-IEA60562
2500mg | 628.00 € |