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CAS 1086111-09-2

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Thiazole-5-boronic acid pinacol ester

Description:
Thiazole-5-boronic acid pinacol ester is an organoboron compound characterized by the presence of a thiazole ring and a boronic acid functional group, which is esterified with pinacol. This compound typically exhibits properties associated with both boron and heterocyclic chemistry. It is often used in organic synthesis, particularly in cross-coupling reactions such as Suzuki-Miyaura coupling, due to the reactivity of the boronic acid moiety. The thiazole ring contributes to the compound's stability and can influence its electronic properties, making it useful in various applications, including pharmaceuticals and agrochemicals. The pinacol ester form enhances the solubility and stability of the boronic acid, facilitating its handling and use in synthetic procedures. Additionally, thiazole derivatives are known for their biological activity, which may extend to this compound, making it of interest in medicinal chemistry. Overall, Thiazole-5-boronic acid pinacol ester is a versatile building block in synthetic organic chemistry, with potential applications in diverse fields.
Formula:C9H14BNO2S
InChI:InChI=1S/C9H14BNO2S/c1-8(2)9(3,4)13-10(12-8)7-5-11-6-14-7/h5-6H,1-4H3
SMILES:CC1(C)C(C)(C)OB(c2cncs2)O1
Synonyms:
  • 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole
  • 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole
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