CAS 108612-45-9: Mizolastine
Description:Mizolastine is an antihistamine medication primarily used to treat allergic conditions such as rhinitis and urticaria. It functions as a selective antagonist of the H1 histamine receptor, effectively alleviating symptoms associated with allergic reactions. Mizolastine is characterized by its relatively long half-life, allowing for once-daily dosing, which enhances patient compliance. The compound exhibits a low potential for sedation compared to first-generation antihistamines, making it suitable for individuals who need to avoid drowsiness. Chemically, Mizolastine is classified as a piperidine derivative and possesses a unique structure that contributes to its pharmacological properties. It is typically administered orally and is well-absorbed in the gastrointestinal tract. The substance is also noted for its anti-inflammatory effects, which may provide additional therapeutic benefits in managing allergic responses. As with any medication, potential side effects may include headache, dry mouth, and gastrointestinal disturbances, though these are generally mild. Overall, Mizolastine represents a valuable option in the management of allergic symptoms with a favorable safety profile.
Formula:C24H25FN6O
InChI:InChI=1S/C24H25FN6O/c1-29(23-26-13-10-22(32)28-23)19-11-14-30(15-12-19)24-27-20-4-2-3-5-21(20)31(24)16-17-6-8-18(25)9-7-17/h2-10,13,19H,11-12,14-16H2,1H3,(H,26,28,32)
InChI key:InChIKey=PVLJETXTTWAYEW-UHFFFAOYSA-N
SMILES:O=C1C=CN=C(N1)N(C)C2CCN(C3=NC=4C=CC=CC4N3CC5=CC=C(F)C=C5)CC2
- Synonyms:
- 2-[[1-[1-[(4-Fluorophenyl)Methyl]Benzoimidazol-2-Yl]-4-Piperidyl]-Methyl-Amino]-3H-Pyrimidin-4-One
- 2-[[1-[1-[(4-Fluorophenyl)methyl]-1H-benzimidazol-2-yl]-4-piperidinyl]methylamino]-4(3H)-pyrimidinone
- 2-[[1-[1-[(4-Fluorophenyl)methyl]benzimidazol-2-yl]piperidin-4-yl]-methylamino]-1H-pyrimidin-6-one
- 2-[[1-[1-[(4-fluorophenyl)methyl]-1H-benzimidazol-2-yl]-4-piperidinyl]methylamino]-4(1H)-pyrimidinone
- 2-[{1-[1-(4-fluorobenzyl)-1H-benzimidazol-2-yl]piperidin-4-yl}(methyl)amino]pyrimidin-4(3H)-one
- 4(1H)-Pyrimidinone, 2-[[1-[1-[(4-fluorophenyl)methyl]-1H-benzimidazol-2-yl]-4-piperidinyl]methylamino]-
- 4(1H)-Pyrimidinone,2-((1-(1-((4-Fluorophenyl)Methyl)-1H-Benzimidazol-2-Yl)-4-P
- 4(3H)-Pyrimidinone, 2-[[1-[1-[(4-fluorophenyl)methyl]-1H-benzimidazol-2-yl]-4-piperidinyl]methylamino]-
- Iperidinyl)Methylamino)-
- Mistamine
- See more synonyms
- Mizolastine HCl
- Mizollen
- Mkc 431
- Sl 850324
- Zolistan
- Mizolastine
