CAS 108700-03-4

diethyl 4-{2-[(1E)-3-tert-butoxy-3-oxoprop-1-en-1-yl]phenyl}-2-[(dimethylamino)methyl]-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride

Description:

Diethyl 4-{2-[(1E)-3-tert-butoxy-3-oxoprop-1-en-1-yl]phenyl}-2-[(dimethylamino)methyl]-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride, with CAS number 108700-03-4, is a complex organic compound characterized by its multi-functional structure, which includes a dihydropyridine core, multiple ester groups, and a dimethylamino substituent. This compound is typically recognized for its potential pharmacological properties, particularly in the context of cardiovascular and neurological research, as it may exhibit activity related to calcium channel modulation. The presence of the tert-butoxy and phenyl groups contributes to its lipophilicity, influencing its solubility and bioavailability. Additionally, the hydrochloride form indicates that it is a salt, which can enhance its stability and facilitate its handling in pharmaceutical formulations. Overall, this compound's intricate structure and functional groups suggest a diverse range of interactions and applications in medicinal chemistry.

Formula: C₂₈H₃₉ClN₂O₆

InChI: InChI=1/C28H38N2O6.ClH/c1-9-34-26(32)23-18(3)29-21(17-30(7)8)25(27(33)35-10-2)24(23)20-14-12-11-13-19(20)15-16-22(31)36-28(4,5)6;/h11-16,24,29H,9-10,17H2,1-8H3;1H/b16-15+;

Synonyms:

• 108700-03-4
• 4-[o-[(E)-2-Carboxyvinyl]phenyl]-2-[(dimethylamino)methyl]-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic acid 4-tert-butyl diethyl ester monohydrochloride
• Gr 53992B
• Gx 1296B
• Taludipine Hydrochloride
• Teludipine Hydrochloride

Teludipine hydrochloride

CAS: 108700-03-4

Teludipine hydrochloride is a drug that has been shown to inhibit the growth of cancer cells in vitro and in vivo. Teludipine hydrochloride inhibits cell proliferation by binding to the extracellular domain of the proprotein convertase subtilisin/kexin type 9 (PCSK9) and preventing it from binding to its receptor. Teludipine hydrochloride also inhibits PCSK9-induced cancer cell death. It has been shown that teludipine hydrochloride can be used as an anti-cancer agent, which may be due to its ability to inhibit PCSK9-induced cellular activation and signal transduction. This drug also binds to disulfide bonds on proteins, which may lead to inhibition of the reaction solution.

Formula: C₂₈H₃₉ClN₂O₆

Purity: Min. 95%

Molecular weight: 535.1 g/mol

Ref: 3D-IEA70003

Teludipine hydrochloride

CAS: 108700-03-4

Teludipine hydrochloride is a blocker of lipophilic calcium channel.

Formula: C₂₈H₃₉ClN₂O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 535.07

Ref: TM-T13117