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CAS 108868-95-7

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andrimid

Description:
Andrimid is a synthetic compound known for its role as a potent inhibitor of bacterial protein synthesis. It is classified as a cyclic peptide and is derived from the natural product family of antibiotics. The molecular structure of andrimid features a unique arrangement of amino acids that contributes to its biological activity. This compound exhibits significant antimicrobial properties, particularly against certain Gram-positive bacteria, making it of interest in the field of medicinal chemistry and antibiotic development. Andrimid functions by interfering with the ribosomal machinery of bacteria, thereby inhibiting the translation process essential for protein production. Its mechanism of action and structural characteristics make it a valuable subject of study for researchers aiming to combat antibiotic resistance. Additionally, andrimid's stability and solubility in various solvents are important factors that influence its potential applications in pharmaceutical formulations. Overall, andrimid represents a promising candidate for further exploration in the development of new antimicrobial agents.
Formula:C27H33N3O5
InChI:InChI=1/C27H33N3O5/c1-5-6-7-8-12-15-21(31)28-20(19-13-10-9-11-14-19)16-22(32)29-24(17(2)3)25(33)23-18(4)26(34)30-27(23)35/h5-15,17-18,20,23-24H,16H2,1-4H3,(H,28,31)(H,29,32)(H,30,34,35)/b6-5+,8-7+,15-12+/t18-,20+,23+,24+/m1/s1
Synonyms:
  • N-(2-Methyl-1-((4-methyl-2,5-dioxo-3-pyrrolidinyl)carbonyl)propyl)-beta-((1-oxo-2,4,6-octatrienyl)amino)benzenepropanamide (3S-(3alpha(R*(R*(2E,4E,6E))),4beta))-
  • Benzenepropanamide, N-(2-methyl-1-((4-methyl-2,5-dioxo-3-pyrrolidinyl)carbonyl)propyl)-beta-((1-oxo-2,4,6-octatrienyl)amino)-, (3S-(3alpha(R*(R*(2E,4E,6E))),4beta))-
  • Andrimid
  • (2E,4E,6E)-N-[(1S)-3-({(2S)-3-methyl-1-[(3R,4S)-4-methyl-2,5-dioxopyrrolidin-3-yl]-1-oxobutan-2-yl}amino)-3-oxo-1-phenylpropyl]octa-2,4,6-trienamide
  • (2E,4E,6E)-N-[(1S)-3-{[(1S)-2-methyl-1-{[(3S,4R)-4-methyl-2,5-dioxopyrrolidin-3-yl]carbonyl}propyl]amino}-3-oxo-1-phenylpropyl]octa-2,4,6-trienamide
  • (βS)-N-[(1S)-2-Methyl-1-[[(3R,4S)-4-methyl-2,5-dioxo-3-pyrrolidinyl]carbonyl]propyl]-β-[[(2E,4E,6E)-1-oxo-2,4,6-octatrienyl]amino]benzenepropanamide
  • Benzenepropanamide, N-[(1S)-2-methyl-1-[[(3R,4S)-4-methyl-2,5-dioxo-3-pyrrolidinyl]carbonyl]propyl]-β-[[(2E,4E,6E)-1-oxo-2,4,6-octatrien-1-yl]amino]-, (βS)-
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  • Andrimid
    Targetmol
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    Andrimid

    CAS:
    <p>Andrimid is a pseudopeptide antibiotic characterized as a polyketide-nonribosomal peptide hybrid product (PK-NRP). It inhibits the carboxyl transfer reaction of bacterial acetyl-CoA carboxylase (ACC), thereby suppressing the biosynthesis of bacterial fatty acids. Andrimid is widely applicable in biomedicine and bio-agriculture.</p>
    Formula:C27H33N3O5
    Color and Shape:Solid
    Molecular weight:479.568

    Ref: TM-TN9058