CAS 1089-77-6

ethane-1,2-diylbis[phenyl(phosphinic acid)]

Description:

Ethane-1,2-diylbis[phenyl(phosphinic acid)], with the CAS number 1089-77-6, is a chemical compound characterized by its dual phosphinic acid functional groups attached to an ethane backbone. This compound features a central ethane chain (C2H4) that connects two phenyl groups, each of which is substituted with a phosphinic acid moiety. The presence of the phosphinic acid groups imparts unique properties, such as the ability to act as a ligand in coordination chemistry and potential applications in catalysis and materials science. Ethane-1,2-diylbis[phenyl(phosphinic acid)] is typically a solid at room temperature and may exhibit moderate solubility in polar solvents due to the presence of the acidic functional groups. Its reactivity can be influenced by the acidity of the phosphinic acid groups, allowing for interactions with various metal ions and organic substrates. Overall, this compound is of interest in both synthetic and applied chemistry, particularly in the development of organophosphorus compounds and their derivatives.

Formula: C₁₄H₁₆O₄P₂

InChI: InChI=1/C14H16O4P2/c15-19(16,13-7-3-1-4-8-13)11-12-20(17,18)14-9-5-2-6-10-14/h1-10H,11-12H2,(H,15,16)(H,17,18)

SMILES: c1ccc(cc1)P(=O)(CCP(=O)(c1ccccc1)O)O

ethane-1,2-diylbis(phenylphosphinic acid)

CAS: 1089-77-6

Formula: C₁₄H₁₆O₄P₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 310.2220

Ref: IN-DA00399J

Ethane-1,2-diylbis(phenylphosphinic acid)

CAS: 1089-77-6

Ethane-1,2-diylbis(phenylphosphinic acid)

Purity: 95%

Molecular weight: 310.23g/mol

Ref: 54-OR1070958

P,P'-Diphenylethylenediphosphinic Acid

Controlled Product

CAS: 1089-77-6

Applications P,P'-Diphenylethylenediphosphinic Acid can bind to ΔF508-CFTR-NBD1 and act as protein-protein interaction inhibitor.
References Odolczyk, N., et al.: EMBO Mol Med, 5, 1484 (2013);

Formula: C₁₄H₁₆O₄P₂

Color and Shape: Neat

Molecular weight: 310.222

Ref: TR-D491585

P,P'-Diphenylethylenediphosphinic acid

CAS: 1089-77-6

P,P'-Diphenylethylenediphosphinic acid (PPEDP) is an ophthalmic drug that binds to the f508del-CFTR protein in the cystic fibrosis transmembrane conductance regulator (CFTR). PPEDP is a triazole and inhibits the activity of tyrosine kinases. PPEDP has been shown to reduce osteopenia by increasing bone mass in animal models. This drug also has antiviral properties and has been shown to be effective against hepatitis C virus infection. PPEDP also reduces inflammation by inhibiting the release of pro-inflammatory cytokines from human osteoblasts.

Formula: C₁₄H₁₆O₄P₂

Purity: Min. 95%

Molecular weight: 310.22 g/mol

Ref: 3D-BAA08977