CAS 108914-10-9

(S)-Methocarbamol

Description:

(S)-Methocarbamol is a chemical compound primarily used as a muscle relaxant in the treatment of muscle spasms and discomfort. It is classified as a carbamate derivative and exhibits central nervous system depressant properties. The substance is typically presented as a white to off-white crystalline powder, which is soluble in water and alcohol, making it suitable for various pharmaceutical formulations. Its mechanism of action involves the inhibition of polysynaptic reflexes in the spinal cord, leading to muscle relaxation. (S)-Methocarbamol is often administered orally or intravenously, depending on the clinical scenario. The compound has a relatively low toxicity profile, but side effects may include dizziness, drowsiness, and gastrointestinal disturbances. As with any medication, it is essential to use (S)-Methocarbamol under medical supervision to ensure safety and efficacy, particularly in patients with pre-existing conditions or those taking other medications. Its chemical structure and stereochemistry contribute to its pharmacological effects, making it an important agent in the management of musculoskeletal pain.

Synonyms:

• 1,2-Propanediol, 3-(2-methoxyphenoxy)-, 1-carbamate, (2S)- (9CI)
• 1,2-Propanediol, 3-(2-methoxyphenoxy)-, 1-carbamate, (S)-

(S)-Methocarbamol

Controlled Product

CAS: 108914-10-9

Applications (S)-Methocarbamol is the inactive componet of methaocarbamol (M225950), a known muscle relaxant. Studies have shown that (+)- R-methocarbamol (M225980) has higher muscle relaxant activity compared with racemic methocarbamol or (-)- S-methocarbamol.
References Souri, E., et al.: J. Pharm. Pharmacol., 51, 853 (1999); Baldi, P., et al.: Bioinformatics, 16, 412 (2000), Kouznetsov, V., et al.: J. Arch. Pharm., 337, 127 (2004)

Formula: C₁₁H₁₅NO₅

Color and Shape: Neat

Molecular weight: 241.24

Ref: TR-M225980